Abstract
Experimental data from some laboratories (increased mitochondrial Ca++ concentration, increased O2 consumption, response to inhibitors, altered enzyme kinetics) point to a deranged mitochondrial function in cystic fibrosis (CF) (Burton and Shapiro, 1989).
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References
Burton, L., Shapiro, B.L., 1989, Evidence for a mitochondrial lesion in cystic fibrosis, Life Sciences, 44:13 27.
Smith, P.K., Krohn, R.I., Hermanson, G.T., Mallia, A.K.,Gartner, F.H., Provenzano, M.D., Fujimoto, E.K., Goeke, N.M., Olson, B.J., Klenk, D.C., 1985, Measurement of protein using Bicinchoninic acid, Anal. Biochem., 150:76.
O’Farrell, P.H., 1975, High resolution two-dimensional electrophoresis of proteins, J. Biol. Chem., 250:4007.
Merril, C.R., Goldman, D., 1981, Ultrasensitive stain for proteins in Polyacrylamide gels shows regional variation in cerebrospinal fluid proteins, Science, 211:1437.
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© 1991 Springer Science+Business Media New York
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Picci, L. et al. (1991). 2D-Electrophoresis of Mitochondrial Proteins from Cystic Fibrosis Patients. In: Tsui, LC., Romeo, G., Greger, R., Gorini, S. (eds) The Identification of the CF (Cystic Fibrosis) Gene. Advances in Experimental Medicine and Biology, vol 290. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5934-0_44
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DOI: https://doi.org/10.1007/978-1-4684-5934-0_44
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