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Advances in Molecular Biology and Targeted Treatment for AIDS pp 79–91Cite as

Role of the TAR Element in Regulating HIV Gene Expression

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Abstract

The human immunodeficiency virus long terminal repeat (HIV LTR) is regulated by multiple cis-acting regulatory sequences.1 Cellular factors which bind to the enhancer, SP1, TATA, and TAR regions are involved in the transcriptional regulation of HIV.2 In addition to cellular proteins, the viral protein, tat, has been shown to greatly stimulate HIV gene expression from the HIV LTR.3, 4

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References

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Author information

Authors and Affiliations

  1. Division of Hematology-Oncology, UCLA School of Medicine, Los Angeles, CA, 90024, USA

    Richard Gaynor

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  1. Richard Gaynor
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Editors and Affiliations

  1. The George Washington University Medical Center, Washington, D.C., USA

    Ajit Kumar

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© 1991 Plenum Press, New York

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Gaynor, R. (1991). Role of the TAR Element in Regulating HIV Gene Expression. In: Kumar, A. (eds) Advances in Molecular Biology and Targeted Treatment for AIDS. GWUMC Department of Biochemistry Annual Spring Symposia. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5928-9_8

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  • DOI: https://doi.org/10.1007/978-1-4684-5928-9_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5930-2

  • Online ISBN: 978-1-4684-5928-9

  • eBook Packages: Springer Book Archive

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