Abstract
AIDS (Acquired Immune Deficiency Syndrome) is the end stage of disease initiated in man by infection with HIV-1 (Human Immunodeficiency Virus) and related viruses. Progression from retroviral infection to AIDS can take years, and may be influenced by immunosuppressive cofactors including drugs of abuse (1,2) and immunostimulatory ones like nutrients (3,4). The role of such compounds in progression to AIDS is difficult to study in humans because of ethical, economical and logistical considerations. While HIV infection has been possible in chimpanzees, it has produced little pathogenesis (6). To investigate simultaneously the effects of immunostimulatory compounds and retroviral infection, it would be advantageous to use a non-primate model.
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© 1991 Plenum Press, New York
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Huang, D.S., Watson, R.R., Chen, GJ., Watzl, B. (1991). The Effects of Canthaxanthin on JB/MS Melanoma Growth During Retroviral Pathogenesis Induced by LP-BM5 Murine Leukemia Virus. In: Friedman, H., Specter, S., Klein, T.W. (eds) Drugs of Abuse, Immunity, and Immunodeficiency. Advances in Experimental Medicine and Biology, vol 288. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5925-8_32
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DOI: https://doi.org/10.1007/978-1-4684-5925-8_32
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