Abstract
Approximately 19 years ago, Falek et al. (1) reported that heroin addicts frequently exhibit abnormally high levels of cytogenetic damage in their T-lymphocytes after mitogenic stimulation in vitro with the plant lectin, phytohemag-glutinin. Later, Madden et al. (2) showed that this damage was probably due to altered DNA-repair capacity of lymphocytes. Less obvious, perhaps, than the genetic implications of these findings were their immunological implications, which, in fact, were significant.
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© 1991 Plenum Press, New York
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Donahoe, R.M. et al. (1991). Effects of Cocaine and Other Drugs of Abuse on Immune Function. In: Friedman, H., Specter, S., Klein, T.W. (eds) Drugs of Abuse, Immunity, and Immunodeficiency. Advances in Experimental Medicine and Biology, vol 288. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5925-8_16
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