Abstract
Oxytetracycline (CTC) is a member of the tetracycline family of broad spectrum antibiotics produced by the filamentous bacteria. These antibiotics have maintained their importance in aspects of human health care (especially the semi-synthetic, doxycycline), but they are also used increasingly in animal healthcare and animal feed supplements.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Behal, V., Hostalek, Z. and Vanek, Z. (1979). Biotechnol. Lett. 1, 177–182.
Bibb, M.J., Ward, J.M. and Hopwood, D.A. (1978) Nature 274, 398–400.
Binnie, C., Warren, M. and Butler, M.J. (1989). 171 (2), 887–895.
Boronin, A.M. & Mindlin, S.Z. (1977). Genetika 8, 125–131.
Butler, M.J., Friend, E.J., Hunter, I.S., Kaczmarek, F.S., Sugden, D.A. and Warren, M. (1989). Mol. Gen. Genet. 215, 231–238.
Chater, K.F. and Bruton, C.J. (1985). EMBO J. 4, 1893–1897.
Distler, J., Brown, C., Ebert, A. and Pipersberg, W. (1987). Malec. & Gen. Genetics 208, 204–210.
Doyle, D., Butler, M.J. and Hunter, I.S. (1988). Heredity 61, 305.
Entsch, B., Nan, Y., Weaich, K. and Scott, K.F. (1988). Gene 71, 279–291
Friend, E.J. & Hopwood, D.A. (1971). J. Gen. Microbiol. 68, 1187–1197.
Hallam, S.E., Malpartida, F.M. and Hopwood, D.A. (1988). Gene 34, 305–320.
Hanley, D.K. and McClure, W.R. (1983). Nuc. Acid Res. 11, 2237–2255.
Hopwood, D.A. (1967). Bacteriological Reviews 31, 373–403.
Hopwood, D.A., Bibb, M.J., Chater, K.F., Kieser, T., Bruton, C.J., Kieser, H.M., Lydiate, D.J., Smith, C.P., Ward, J.M. and Schrempf, M. (1985). Genetic Manipulation of Streptomyces; a laboratory manual. John Innes Foundation, Norwich.
Hopwood, D.A. and Sherman, D.H. (1990). Ann. Rev. Genetics 24 (in press).
Ishada, I., Obinata, M. and Deguchi, T. (1988). J. Biel. Chem. 262, 2895–2899.
Kieser, T., Hopwood, D.A., Wright, H.M. and Thompson, C.J. (1982). Mol. Gen. Genet. 185, 223–238.
Kuo, M-S.T., Yurek, D.A., Coats, J.H. and Li, G.P. (1989). J. Antibiotics 42 (3), 475–473.
McCormick, J.R.D. and Jensen, E.R. (1969). J. American Chem. Soc. 91, 206–221
McCormick, J.R.D. (1969). In: Genetics and Breeding of Streptomyces, Sennart, G. and Alacevic, M., Yugoslav Academy of Sciences and Arts, Zagreb. P. 163.
Malpartida, F., Hallam, S.E., Kieser, H.M., Motamedi, H., Hutchinson, C.R., Butler, M.J., Sugden, D.A., Warren, M., McKillop, C., Bailey, C.R., Humphreys, G.O. and Hopwood, D.A. (1987). Nature 325, 818–820.
Manavathu, E.K., Hiratsuko, K. and Taylor, D.E. (1988). Gene 62, 17–26.
Miller, P.A., Sjolander, N.O., Nalesnyk, S., Arnold, N., Jchnson,S., Doerschuk, A.D. and McCormick, J.R.D. (1960). J. Am. Chem. Soc. 32, 5002–5003.
Murakami, T., Anzai, H., Imari, S., Satch, A., Nagaoka, K. and Thompson, C.J. (1986). Mol. Gen. Genetics 205, 42–50.
Ohnuki, T., Imanaka, T. and Aiba, S. (1985b). J. Bacterial. 164, 185–194.
Ohnuki, T., Katoh, T., Imanaka, T. and Alba, S. (1985a). J. Bacterial. 161, 1010–1016.
Pigac, J. and Alacevic, M. (1979). Period. Biol. 81, 575–82.
Pigac, J., Hranueli, D., Smokvina, T. and Alacevic, M. (1982). Appl. Environ. Mircobiol. 44, 1178–1186.
Reynes, J-P., Calmeb, T., Drocourt, D., and Tiraby, G. (1988). J.Gen. Microbial. 34, 585–598.
Rhodes, P.M., Winskill, N., Friend, E.J. and Warren, M. (1981). J. Gen. Microbicl. 124, 329–398.
Rhodes, P.M., Hunter, I.S., Friend, E.J. and Warren, M. (1984). Biochem. Soc. Trans. 12, 586–587.
Salyers, A.A., Speer, B.S. and Shoemaker, N.B. (1990). Mol. Microbial. 4 (1), 151–156.
Seno, E.T. and Baitz, R.H. (1982) Antimicrobiol Agents and Chemotherapy 21, 758–763.
Sinclair, A.C., Schenk, J. and Frida, H.H. (1962). Antimicrobial Agents & Chemotherapy 1961, 892–895.
Sherman, D.H., Malpartida, F., Kieser, H.M., Bibb, M.J. and Hopwood D.A. (1989). EMBO J. 8, 2717–2726.
Sanchez-Pescader, R., Brown, J. T., Roberts, M. and Urdia, M.S. (1988). Nuc. Acid Res. 16, 1216–1217.
Stanzak, R., Matsushima, P., Baltz, R.H. and Rao, R.N. (1986). Biotechnology 4, 229–232.
Stein, D., Kendall, K.J. and Cohen, S.N. (1989). J. Bacteriol. 171, 5768–5775.
Thomas, R, and Williams, D.J. O. J. Chem.. Chem. Comm. 677–679.
Vancurova, I., Vold, J., Flieger, M., Neuzil, J., Novotna, J., Vlach, J. and Behal, V. (1988). Biochem.1983 J. 253, 263–267
Westpheling, J.E., Raines, M. and Losick, R. (1985). Nature 313, 22–27.
Wierenga, R.K., de Jong, R.J., Kalk, K.H., Hol, W.G. and Dreuth, R. (1979). J. Mol. Biol. 131, 55–73.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1991 Plenum Press, New York
About this chapter
Cite this chapter
McDowall, K.J., Doyle, D., Butler, M.J., Binnie, C., Warren, M., Hunter, I.S. (1991). Molecular Genetics of Oxytetracycline Production by Streptomyces rimosus . In: Baumberg, S., Krügel, H., Noack, D. (eds) Genetics and Product Formation in Streptomyces . Federation of European Microbiological Societies Symposium Series, vol 55. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5922-7_13
Download citation
DOI: https://doi.org/10.1007/978-1-4684-5922-7_13
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-5924-1
Online ISBN: 978-1-4684-5922-7
eBook Packages: Springer Book Archive