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Effects of Elevated Temperature on the Epididymis and Testis: Experimental Studies

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Book cover Temperature and Environmental Effects on the Testis

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 286))

Abstract

The testis has been the natural focus of attention in considering the effects of elevated temperatures on male reproduction. In all mammals studied, including man, the germinal epithelium of the scrotal testis is acutely sensitive to an increase of only a very few degrees, and much effort has been devoted to analysis of this response (Waites and Setchell, 1969; Vandemark and Free, 1970; Harrison, 1975; Kandeel and Swerdloff, 1988). Considerable attention has been given also to the broader biological question as to why the testes of a majority of mammals should need to function at temperatures somewhat below that of the body. However, a focus on the physiology of the testis per se has produced no satisfactory explanation of this phenomenon.

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References

  • Amann, R.P. 1981. A critical review of methods for evaluation of spermatozoa from seminal characteristics.J. Androl.. 2: 37.

    Google Scholar 

  • Amann, R.P., Koefoed-Johnson, H.H. and Levi, H. 1965. Excretion pattern of labelled spermatozoa and the timing of spermatozoa formation and epididymal transit in rabbits injected with thymidine 3H.J. Reprod. Fertil., 10: 169.

    Article  PubMed  CAS  Google Scholar 

  • Bedford, J.M. 1977a. Sperm/egg interaction: the specificity of human spermatozoa.Anat. Rec. 188: 477.

    Article  PubMed  CAS  Google Scholar 

  • Bedford, J.M. 1977b. Evolution of the scrotum: the epididymis as the prime mover? In: “Evolution and Reproduction”, J.H. Calaby and C.H. Tyndale-Biscoe (eds.), Aust. Acad. Sci., Canberra, p. 171.

    Google Scholar 

  • Bedford, J.M. 1978a. Anatomical evidence for the epididymis as the prime mover in the evolution of the scrotum.Am. J. Anat., 152: 483.

    Article  PubMed  CAS  Google Scholar 

  • Bedford, J.M. 1978b. Influence of abdominal temperature on epididymal function in the rat and rabbit,Am J. Anat., 152: 509.

    Article  PubMed  CAS  Google Scholar 

  • Bedford, J.M. 1990. Fertilization mechanisms in animals and man: current concepts. In: “Establishment of a Human Pregnancy”, R.G. Edwards (ed.), Raven Press, New York, p. 115.

    Google Scholar 

  • Bedford, J.M. 1991. Co-evolution of mammalian gametes. In: “A Comparative Overview of Mammalian Fertilization”, B.S. Dunbar and M.G. O’Rand (eds.), Plenum Press, New York, in press.

    Google Scholar 

  • Bedford, J.M., Calvin, H. and Cooper, G.W. 1973. The maturation of spermatozoa in the human epididymis.J. Reorod. Fertil. Suppl. 18: 199.

    CAS  Google Scholar 

  • Bedford, J.M., Berrios, M. and Dryden, G.L. 1982. Biology of the scrotum, IV. Testis location and temperature sensitivity.J. Exp. Zool., 224: 379.

    Article  PubMed  CAS  Google Scholar 

  • Bedford, J.M. and Yanagimachi, R. 1991. Epididymal storage at abdominal temperature reduces the time required for capacitation of hamster spermatozoa.J. Reprod. Fertil., In Press.

    Google Scholar 

  • Brooks, D.E. 1973. Epididymal and testicular temperature in the unrestrained conscious rat.J. Reprod. Fertil., 35: 157.

    Article  PubMed  CAS  Google Scholar 

  • Corselli, J. and Talbot, P. 1987. In vitro penetration of hamster oocyte-cumulus complexes using physiological numbers of sperm.Dev. Biol., 122: 222.

    Article  Google Scholar 

  • Cummins, J.M. 1990. Evolution of sperm form: levels of control and competition. In: “Fertilization in Mammals”, B.D. Bavister, J.M. Cummins and E.R.S. Roldan (eds.), Serono Symposia, U.S.A., p. 51.

    Google Scholar 

  • Ehrenberg, L., Ehrenstein, G. and Hedgran, A. 1957. Gonad temperature and spontaneous mutation rate in man.Nature. London, 180: 1433.

    Article  PubMed  CAS  Google Scholar 

  • Esponda, P. and Bedford, J.M. 1986. The influence of body temperature and castration on the protein composition of fluid in the rat cauda epididymidis.J. Reprod. Fertil., 78: 505.

    Article  PubMed  CAS  Google Scholar 

  • Esponda, P., Regalado, F. and Nieto, A. 1990. Effects of temperature and castration on the synthesis of secretory proteins in the rabbit cauda epididymidis. In: “Fertilization in Mammals”, B.D. Bavister, J.M. Cummins and E.R.S. Roldan (eds.), Serono Symposia, U.S.A., p. 416.

    Google Scholar 

  • Foldesy, R.G. and Bedford, J.M. 1982. Biology of the scrotum, 1. Temperature and androgen as determinants of the sperm storage capacity of the rat cauda epididymidis.Biol. Reorod., 26: 673.

    Article  CAS  Google Scholar 

  • Glover, T.D. 1960. Spermatozoa from the isolated cauda epididymidis of rabbits and some effects of artificial cryptorchidism.J. Reorod. Fertil., 1: 121.

    Article  Google Scholar 

  • Goodrowe, K.L., Howard, J.G., Schmidt, P.M. and Wildt, D.E. 1989. Reproductive biology of the domestic cat with special reference to endocrinology, sperm function and in vitro fertilization.J. Reorod. Fertil. Suppl. 39: 73.

    CAS  Google Scholar 

  • Harrison, R.G. 1975. Effect of temperature on the mammalian testis. In: “Handbook of Physiology, Section 7: Endocrinology, Volume V, Male Reproductive System”, D.W. Hamilton and R.W. Greep (eds.), American Physiological Society, Washington, D.C., p. 219.

    Google Scholar 

  • Holstein, A.F. 1975. Morphologische Studien an abnormen spermatiden und spermatozoen des menschen.Virchows Arch (Pathol. Anat.). 367: 93.

    Article  CAS  Google Scholar 

  • Johnson, L. and Varner, D.D. 1988. Effect of daily Spermatozoon production but not age on transit time of spermatozoa through the human epididymis.Biol. Reorod., 39: 812.

    Article  CAS  Google Scholar 

  • Kandeel, F.R. and Swerdloff, R.S. 1988. The role of temperature in regulation of spermatogenesis and the use of heating as a method for contraception.Fertil. Steril., 49: 1.

    PubMed  CAS  Google Scholar 

  • Kenagy, G.J. and Trombulak, S.C. 1986. Size and function of mammalian testes in relation to body size.J. Mammal., 67: 1.

    Article  Google Scholar 

  • Orgebin-Crist, M.-C. 1965. Passage of spermatozoa labelled with thymidine 3H through the ductus epididymidis of the rabbit.J. Reorod. Fertil., 10: 241.

    Article  CAS  Google Scholar 

  • Overstreet, J.W. and Hembree, W.C. 1976. Penetration of the zona pellucida of non-living human oocytes by spermatozoa in vitro.Fertil. Steril., 27: 815.

    PubMed  CAS  Google Scholar 

  • Overstreet, J.W., Gould, J.E., Katz, D.F. and Hanson, F.W. 1980. In vitro capacitation of human spermatozoa after passage through a column of cervical mucus.Fertil. Steril., 34: 604.

    PubMed  CAS  Google Scholar 

  • Perreault, S.D. and Rogers, B.J. 1982. Capacitation patterns of human spermatozoa.Fertil. Steril., 38: 258.

    PubMed  CAS  Google Scholar 

  • Rasweiler, J.J. and Bedford, J.M. 1982. Biology of the scrotum. III. Effects of abdominal temperature upon the epithelial cells of the rat cauda epididymidis.Biol. Reorod., 26: 691.

    Article  Google Scholar 

  • Robaire, B. and Hermo, L. 1988. Efferent ducts, epididymis, and vas deferens: structure, functions and their regulation. In: “The Physiology of Reproduction”, Vol. I, E. Knobil and J.D. O’Neill (eds.), Raven Press, New York, p. 999.

    Google Scholar 

  • Short, R.V. 1979. Sexual selection and its component parts, somatic and genital selection, as illustrated by man and the great apes.Adv. Stud. Behav., 9: 131.

    Article  Google Scholar 

  • Short, R.V., Mann, T. and Hay, M.F. 1967. Male reproductive organs of the African elephant,Loxodonta africana.J. Reorod. Fertil., 13: 517.

    Article  CAS  Google Scholar 

  • Vandemark, N.L. and Free, M.J. 1970. Temperature effects. In: “The Testis”, Vol. III, A.D. Johnson, W.R. Gomes and N.L. Vandemark (eds.), Academic Press, New York, p. 233.

    Google Scholar 

  • Waites, G.M.H. and Setchell, B.P. 1969. Some physiological aspects of the function of the testis. In: “The Gonads”, K.W. McKerns (ed.), Appleton, New York, p. 649.

    Google Scholar 

  • White, D.R., Phillips, D.M. and Bedford, J.M. 1990. Factors affecting the acrosome reaction in human spermatozoa.J. Reorod. Fertil., 90: 71.

    Article  CAS  Google Scholar 

  • Wong, P.Y.D., Au, C.L. and Bedford, J.M. 1982. Biology of the scrotum, II. Suppression by abdominal temperature of transepithelial ion and water transport in the cauda epididymidis.Biol. Reorod., 26: 683.

    Article  CAS  Google Scholar 

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© 1991 Plenum Press, New York

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Bedford, J.M. (1991). Effects of Elevated Temperature on the Epididymis and Testis: Experimental Studies. In: Zorgniotti, A.W. (eds) Temperature and Environmental Effects on the Testis. Advances in Experimental Medicine and Biology, vol 286. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5913-5_3

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  • DOI: https://doi.org/10.1007/978-1-4684-5913-5_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5915-9

  • Online ISBN: 978-1-4684-5913-5

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