Chronic Scrotal Hypothermia

  • Adrian W. Zorgniotti
  • Andrew I. Sealfon
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 286)


The Testicular Hypothermia Device (THD) was conceived to test the theory that an intrinsic defect in testicular thermoregulation causes elevation of intrascrotal temperature and results in subfertile semen (Zorgniotti et al., 1980, 1986). When it was found that lowering temperature about 2.0°C by a prototype THD resulted in semen improvement and pregnancy in the wives of infertile men, the therapeutic potential was realized. The THD is a cotton scrotal covering which lowers temperature by controlled evaporation of water from its surface (Figure 1).


Infertile Couple Tinea Cruris Idiopathic Infertility Control Evaporation Scrotal Temperature 
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  1. Basralian, K.R. et al. 1987. Duration of involuntary infertility and subsequent pregnancy.Urology, 29: 635.PubMedCrossRefGoogle Scholar
  2. Lee, H.W. et al. 1984. Effect of varicocelectomy on spermatogenesis. In: “Varicocele and male fertility II”, M. Glezerman (ed.), Springer Verlag, Berlin.Google Scholar
  3. Zorgniotti, A.W. et al. 1980. Chronic scrotal hypothermia as a treatment for poor semen quality.Lancet, I: 904.CrossRefGoogle Scholar
  4. Zorgniotti, A.W. et al. 1986. Chronic scrotal hypothermia: results in 90 infertile couples.J. Uro l., 135: 944.Google Scholar

Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Adrian W. Zorgniotti
    • 1
  • Andrew I. Sealfon
    • 2
  1. 1.Department of UrologyNew York University School of MedicineUSA
  2. 2.Repro-Med Systems, Inc.MiddletownUSA

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