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Lipoprotein A-I Containing Particles

  • Nicolas Duverger
  • Nordine Ghalim
  • Nathalie Theret
  • Philippe Duchateau
  • Gustave Aguie
  • Gérard Ailhaud
  • Graciela Castro
  • Jean-Charles Fruchart
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 285)

Abstract

Many epidemiological studies have indicated that the plasma level of high density lipoproteins (HDL) is inversely correlated with the risk for coronary artery disease1. It has been hypothesized that HDL exerts this protective effect by the “reverse” transport of excess cholesterol from peripheral tissues to the liver2.

Keywords

High Density Lipoprotein High Density Lipoprotein Cholesterol Efflux Lipoprotein Particle Lecithin Cholesterol Acyl Transferase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    T. Gordon, W.P. Castelli, M.C. Hjortland, W.B. Kannel, T.R. Dawber, High density lipoprotein as protective factor against coronary heart disease, Am. J. Med, 62:707 (1977).PubMedCrossRefGoogle Scholar
  2. 2.
    J. A. Glomset, The plasma lecithin-cholesterol acyl transferase reaction, J. Lipid Res. 9:155 (1968).PubMedGoogle Scholar
  3. 3.
    G. R. Castro, and C.F. Fielding, Evidence for the distribution of apolipoprotein E between lipoprotein classes in human normo cholesterolemic plasma and for the origin of unassociated apolipo protein E (LpE), J. Lipid Res. 25:58 (1984).PubMedGoogle Scholar
  4. 4.
    R. Barbaras, P. Puchois, J.C. Fruchart, and G. Ailhaud, Cholesterolefflux from cultured adipose cells is mediated by LpA-I particles but not by LpA-I:A-II particles, Biochem. Biophys. Res. Commun142:63 (1987).PubMedCrossRefGoogle Scholar
  5. 5.
    A. Steinmetz, R. Barbaras, N. Ghalim, V. Clavey, J.C. Fruchart, and G. Ailhaud, Human apolipoprotein A-IV binds to apolipoprotein A-I/A-II receptor sites and promotes cholesterol efflux from adipose cells, J. Biol. Chem. 265:7859 (1990).PubMedGoogle Scholar
  6. 6.
    C. Delbart, N. Theret, G. Ailhaud, J.C. Fruchart, Phosphatidylcholine breakdown during receptor binding of HDL3, 62nd Scientific Sessions of American Heart Association, New-Orleans, 13–16 novembre 1989, Circulation, 80/4, supplement II, II-487, abstract 1938 (1989).Google Scholar
  7. 7.
    A. Nouvelot, G. Sezille, P. Dewailly, J.C. Fruchart, Chromatographie monodimensionnelle des lipides polaires sur couche mince de gel de silice en gradient discontinu d’humidite, Revue Francaise des Corps Gras 7:251 (1977).Google Scholar
  8. 8.
    L. Hagenfelt, A gas chromatography method for the determination on individual free fatty acids in plasma, Clin. Chim. Acta 13:266 (1966).CrossRefGoogle Scholar
  9. 9.
    C. H. Chen and J.J. Albers, Characterization of proteoliposomes containing apolipoprotein A-I : a new substrate for the measurement of lecithin cholesterol acyl transferase activity, J. Lipid Res23:680 (1982).PubMedGoogle Scholar
  10. 10.
    J. F. Craig, D.P. Via, B.C. Sharril, L.A. Labar, W.W. Mantulin, A.M. Gotto, and L. Smith, Incorporation of defined cholesteryl esters into lipoproteins using cholesterol ester-rich microemulsions, J. Biol. Chem. 257:330 (1982).PubMedGoogle Scholar
  11. 11.
    E. Koren, P. Puchois, P. Alaupovic, J. Fesmire, A. Kandoussi, J.C. Fruchart, Quantification of two different types of apolipoprotein A-I containing lipoprotein particles in plasma by enzyme linked differential antibody immunosorbent assay, Clin. Chem. 33:38 (1987).PubMedGoogle Scholar
  12. 12.
    H. J. Parra, H. Mezdour, N. Ghalim, J.M. Bard, J.C. Fruchart, Differential electroimmunoassay on ready-to-use plates for human LpA-I lipoprotein particles, Clin. Chem. in press (1990).Google Scholar
  13. 13.
    P. Puchois, A. Kandoussi, P. Fievet, J.L. Fourrier, M. Bertrand, E. Koren, J.C. Fruchart, Apolipoprotein A-I containing lipoproteins in coronary artery disease, Atherosclerosis 68:35 (1987).PubMedCrossRefGoogle Scholar
  14. 14.
    G. Luc, J.M. Bard, S. Lussier-Cacan, H.J. Parra, J.C. Fruchart, J. Davignon, High density lipoprotein particles in octogenarians, Metabolism in press (1990).Google Scholar
  15. 15.
    P. Amouyel, H.J. Parra, D. Boute, J.M. Bard, D. Isorez, D. Barbier, J.C. Fruchart, G. Zylberberg, Inlfuence des antécédents cardio vasculaires familiaux sur le profil lipoprotéique d’une population issue de la métropole lilloise, XVeme Réunion de l’ADELF, Bordeaux, 12–15 septembre 1989.Google Scholar
  16. 16.
    N. Ghalim, P. Puchois, G. Zylberberg, P. Fievet, C. Demarquilly, J.C. Fruchart, Effect of alcohol intake on human apolipoproteins A-I containing lipoproteins subtractions, Arch. Int. Med, in press (1990).Google Scholar

Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Nicolas Duverger
    • 1
  • Nordine Ghalim
    • 1
  • Nathalie Theret
    • 1
  • Philippe Duchateau
    • 1
  • Gustave Aguie
    • 1
  • Gérard Ailhaud
    • 2
  • Graciela Castro
    • 1
  • Jean-Charles Fruchart
    • 1
  1. 1.SERLIA et U. INSERM 325Institut PasteurLille CédexFrance
  2. 2.Centre de BiochimieParc ValroseNiceFrance

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