Abstract
Peroxidation of membrane lipids is thought be a dynamic process which is ongoing in virtually all cells. Under normal conditions, cellular lipid peroxidation is well regulated and, as noted in a recent review (Esterbauer. et al. , 1990), is always associated with the formation of numerous and chemically diverse aldehydic products. Malondialdehyde (MDA) and trans-4-hydroxy-2-nonenal (HNE) are classified as major products of lipid peroxidation since they are present in the greatest quantities during peroxidation of cellular membrane lipids while trans-2-hexenal, acrolein and crotonaldehdye are representative of minor products of lipid peroxidation thought to be formed in significantly smaller quantities.
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Petersen, D.R., Hjelle, J.J., Mitchell, D.Y. (1990). Aldehydic Products of Lipid Peroxidation: Substrates or Inhibitors of Hepatic Aldehyde Dehydrogenase?. In: Weiner, H., Wermuth, B., Crabb, D.W. (eds) Enzymology and Molecular Biology of Carbonyl Metabolism 3. Advances in Experimental Medicine and Biology, vol 284. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5901-2_9
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DOI: https://doi.org/10.1007/978-1-4684-5901-2_9
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