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Alcohol Dehydrogenase Gene Expression and Cloning of the Mouse χ-Like ADH

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Enzymology and Molecular Biology of Carbonyl Metabolism 3

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 284))

Abstract

Some of the differences between individuals in the metabolism of alcohol and in their susceptibility to alcoholism or its complications may be due to differences in the metabolism of ethanol. The amount of each different isozyme expressed will influence the overall alcohol dehydrogenase activity in a given tissue, and could play an important role in mediating or modulating the effects of ethanol. For these reasons, we have been studying the structure and expression of the mammalian alcohol dehydrogenases.

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Author information

Authors and Affiliations

  1. Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, 46202-5122, USA

    Howard J. Edenberg, Celeste J. Brown, Lucinda G. Carr, Wei-Hsien Ho & Man-Wook Hur

Authors
  1. Howard J. Edenberg
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  2. Celeste J. Brown
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  3. Lucinda G. Carr
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  4. Wei-Hsien Ho
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  5. Man-Wook Hur
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Editor information

Editors and Affiliations

  1. Department of Biochemistry, Purdue University, West Lafayette, Indiana, 47907, USA

    Henry Weiner

  2. Chemisches Zentrallabor, Inselspital, Bern, CH 3010, Switzerland

    Bendicht Wermuth

  3. Indiana University School of Medicine and Veterans Administration Medical Center, Indianapolis, Indiana, 46202, USA

    David W. Crabb

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© 1990 Plenum Press, New York

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Edenberg, H.J., Brown, C.J., Carr, L.G., Ho, WH., Hur, MW. (1990). Alcohol Dehydrogenase Gene Expression and Cloning of the Mouse χ-Like ADH. In: Weiner, H., Wermuth, B., Crabb, D.W. (eds) Enzymology and Molecular Biology of Carbonyl Metabolism 3. Advances in Experimental Medicine and Biology, vol 284. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5901-2_27

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  • DOI: https://doi.org/10.1007/978-1-4684-5901-2_27

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5903-6

  • Online ISBN: 978-1-4684-5901-2

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