Skip to main content

Measuring Contact Stress with 19F-NMR Spectroscopy

  • Chapter
Polymer Gels
  • 569 Accesses

Abstract

Increased static contact stress is associated with tissue damage in vivo and in vitro. It could be caused by edema (for example, in normal hydrocephalus) or a growing tumor which displaces surrounding tissue. Measurement of contact stress is inherently invasive, however, it can be less traumatic with a sensor having no wires or leads. One goal of this chapter is to propose that NMR spectroscopy can perform the function of a telemetry system provided that an in-dwelling transducer can convert the desired physical quantity (such as applied stress) to an NMR detectable chemical change. Previously, it was observed that compressing polyelectrolyte gels could cause a redistribution of mobile ions that is measurable with NMR spectroscopy [1]. In the sensor described below, the applied stress is inferred from a non-invasive 19F-NMR spectroscopic measurement of pH.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. P. J. Basser, J. Eng, & P. Chiarelli, A Polymer Based Method to Measure Contact Stress, Proceedings of the Society of Polymer Science, Japan, 20–23, (1989)

    Google Scholar 

  2. T.Tanaka, D.J.Fillmore, Kinetics of Swelling of Gels, J. Chem. Phys., 70(3), 1214–1218 (1978)

    Article  Google Scholar 

  3. M. A. Biot, Consolidation Settlement Under a Rectangular Load Distribution, J. Appl. Phys., 12(2), 426 (1941)

    Article  Google Scholar 

  4. M. A. Biot, General Theory of Three-Dimensional Consolidation, J. Appl. Phys., 12, 155 (1941)

    Article  Google Scholar 

  5. M. A. Biot, Theory of Elasticity and Consolidation of a Porous Anisotropic Solid, J. Appl. Phys., 26 (2), 182–185, (1955)

    Article  CAS  Google Scholar 

  6. M. A. Biot, G. Willis, The Elastic Coefficients of the Theory of Consolidation, J. Appl. Mech. 24, 594 (1957)

    Google Scholar 

  7. W. Press, B. Flaherty, et al., “Numerical Recipes”, Cambridge University Press

    Google Scholar 

  8. E. H. Frank, A.J. Grodzinsky, Cartilage Electromechanics-II. A Continuum Model of Cartilage Electrokinetics and Correlation with Experiments, J. Biomechanics, 20 (6), 629–639 (1987)

    Article  CAS  Google Scholar 

  9. P. E. Grimshaw, J. H. Nussbaum, A.J. Grodzinsky, and M. L. Yarmush, “Kinetics of Electrically and Chemically Induced Swelling in Polyelectrolyte Gels”, Jour. Chem. Phys. (in press)

    Google Scholar 

  10. E. Becker, “High Resolution NMR, Theory and Applications”, 2nd Edition Academic Press, (1980)

    Google Scholar 

  11. C Deutsch, J. S. Taylor, D. F. Wilson, “Regulation of intracellular pH by human peripheral blood lymphocytes as measured by 19F NMR”, Proc. Natl. Acad. Sci. 79, 7944–7948, (1982)

    Article  PubMed  CAS  Google Scholar 

  12. C. Deutsch, T. Kashiwagura, J. Taylor, D. Wilson, M, Erecinska, “The effect of Glucagon and Adrenergic Agonists on Intracellular pH of Isolated Rat Hepatocytes”, Jour. Biol. Chem., 260 (11), (1985)

    Google Scholar 

  13. R. Weast, M. Astle, ed. “Handbook of Chemistry and Physics”, F-51, 1983, CRC Press, Inc.

    Google Scholar 

  14. J. Riŏka, T. Tanaka, “Swelling of Ionic Gels: Quantitative Performance of the Donnan Theory”, Macromolecules, 17 (12), 2916–2921 (1984)

    Article  Google Scholar 

  15. D. LeBihan, J. Delannoy, R. L. Levin, “Non-invasive temperature mapping using magnetic resonance imaging of molecular diffusion”, Radiology, 171, 853–857, (1989)

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1991 Plenum Press, New York

About this chapter

Cite this chapter

Basser, P.J. (1991). Measuring Contact Stress with 19F-NMR Spectroscopy. In: DeRossi, D., Kajiwara, K., Osada, Y., Yamauchi, A. (eds) Polymer Gels. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5892-3_20

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-5892-3_20

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5894-7

  • Online ISBN: 978-1-4684-5892-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics