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Regeneration of Skeletal Muscle Fibers after Necrosis

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Myoblast Transfer Therapy

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 280))

Abstract

I am going to review the normal process of regeneration after necrosis in skeletal muscle and compare it with what happens in Duchenne dystrophy. Dr. Karpati and I have devised an experimental method for producing a focal lethal injury of skeletal muscle qells in which the sequence of steps can be closely followed. We call it experimental micropuncture injury, because the muscle cells are transfixed by a fine tungsten wire with a 10µm tip. All fibers that are pierced go on to necrosis.

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References

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© 1990 Plenum Press, New York

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Carpenter, S. (1990). Regeneration of Skeletal Muscle Fibers after Necrosis. In: Griggs, R.C., Karpati, G. (eds) Myoblast Transfer Therapy. Advances in Experimental Medicine and Biology, vol 280. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5865-7_3

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  • DOI: https://doi.org/10.1007/978-1-4684-5865-7_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5867-1

  • Online ISBN: 978-1-4684-5865-7

  • eBook Packages: Springer Book Archive

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