Abstract
The current overview presents HSV-1 pathogenicity and latency from the point of view of a practicing ophthalmologist. It begins with the premise that “man is the measure of all things.” The devastation wrought by herpes simplex virus type 1 (HSV-1) in the human eye is both significant and widespread. HSV-1 is the leading infectious cause of corneal blindness in the industrialized world, and there are over 300,000 cases of herpetic eye infection annually in the United States (1). Our goal in ophthalmology is to reduce and ultimately prevent the visual loss due to herpes simplex eye infections.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Kaufman, H. E. (1978) Invest. OphthalmoL Visual Sci. 17, 941–957.
Pavan-Langston, D. (1987) in The Cornea, eds. Smolin, G. S. and Thoft, R. A. (Little, Brown, Boston ), pp. 240–254.
Buddingh, G. J., Schrum, D. I. and Lanier, J. C. (1953) Pediatrics 11, 595.
Croen, K. D., Ostrove, J. M., Dragovic, L. J., Smialek, J. E. and Strauss, S. E. (1987) N. Engl. J. Med 317, 1427–1432.
Gordon, Y. J., Johnson, B., Romanowski, E. and Araullo-Cruz, T. (1988) J. Virol. 62, 1832–1835.
Stevens, J. G., Haan, L, Porter, D. D., Cook, M. L. and Wagner, E. K. (1988) J. Infect Dis. 158, 117–123.
Carroll, J. M., Martola, E. M., Laibson, P. R. and Dohlman, C. (1967) Am. J. Ophthalmol. 63, 103–107.
Gordon, Y. J., Armstrong, J. A. and Brown, S. I. (1983)Am. J. Ophthalmot 95, 175–181.
Gordon, Y. J., Cheng, K. P., Araullo-Cruz, T., Romanowski, E., Johnson, B. J. and Blough, H. A. (1986) Cur: Eye Res. 5, 93–99.
Stevens, J. G., Wagner, E. K., Devi-Rao, G. B., Cook, M. L. and Feldman, L. T. (1987) Science (Washington, D. C., 1883-) 235, 1056–1059.
Rock, D. L, Nesburn, A. B., Ghiasi, H., Ong, J., Lewis, T. L., Lokensgard, J. R and Wechsler, S. L. (1987) J. Vim!. 61, 3820–3826.
Kaufman, H. E., Brown, D. C. and Ellison, E. M. (1967) Science (Washington, D. C., 1883-) 156, 1628–1629.
Wheeler, C. E. (1975) J. Invest. DernatoL 65, 341–346.
Hoyt, C. S. and Billson, F. A. (1976) Lancet 2, 1364–1365.
Bloomfield, S. E. and Lopez, C. (1980) Ophthalmology (Rochester, Minn.) 87, 1226–1235.
Harbour, D. A., Hill, T. J. and Blyth, W. A. (1983) J. Gen. Virol. 64, 1491–1498.
Blyth, W. A., Harbour, D. A. and Hill, T. J. (1980) Infect. Immun. 29, 902–907.
Shimomura, Y., Gangarosa, L. P., Katoaka, M. and Hill, J. M. (1983) Invest. Ophthalmol Visual Sci 24, 1588–1594.
Gordon, Y. J., Araullo-Cruz, T., Romanowski, E., Ruziczka, L., Balouris, C., Oren, J., Cheng, K. P. and Kim, S. (1986) Invest. OphthalmoL Visual Sci. 27, 1230–1234.
Gordon, Y. J., Romanowski, E. and Araullo-Cruz, T. (in press) Invest. OphthalmoL Visual Sci.
Roizman, B. and Sears, A. (1987) Annu. Rev. MicrobioL 41, 543–572.
Sachs, W. R. and Schaffer, P. A. (1987) J. Virol. 61, 829–839.
Gordon, Y. J., Romanowski, E., Balouris, C. and Araullo-Cruz, T. (in press) Invest. OphthalmoL Visual Sci
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Plenum Press, New York
About this chapter
Cite this chapter
Gordon, Y.J. (1990). Pathogenesis and Latency of Herpes Simplex Virus Type 1 (HSV-1): An Ophthalmologist’s View of the Eye as a Model for the Study of the Virus-Host Relationship. In: Lopez, C., Mori, R., Roizman, B., Whitley, R.J. (eds) Immunobiology and Prophylaxis of Human Herpesvirus Infections. Advances in Experimental Medicine and Biology, vol 278. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5853-4_21
Download citation
DOI: https://doi.org/10.1007/978-1-4684-5853-4_21
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-5855-8
Online ISBN: 978-1-4684-5853-4
eBook Packages: Springer Book Archive