Smoking and Blood Rheology

  • Edzard Ernst
  • Wolfgang Koenig
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 273)


Smoking limits blood fluidity as measured by in vitro methods such as blood and plasma viscosities, hematocrit (for the present purpose interchangeable with hemoglobin), red cell aggregation and blood cell filtration (1). Blood rheology, in turn, can determine blood flow (2) and might play a role in the development of atherosclerosis (3). The present paper summarizes our work concerning the effects of smoking on blood rheology. Firstly, a hemorheological deficit is verified by means of an epidemiological study. Secondly, the dose dependency of the detrimental effects are analyzed in a clinical trial. Thirdly, an intervention study shows that most of the rheological effects are reversible upon cessation of smoking.


Smoking History Total Serum Protein Plasma Viscosity Female Smoker Blood Rheology 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Edzard Ernst
    • 1
  • Wolfgang Koenig
    • 2
  1. 1.Dept. Physical Medicine and Rehabilitation Medical SchoolGermany
  2. 2.Dept. Internal MedicineUniversity of UlmGermany

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