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Herpes Simplex Virus Type 1 Transcription during Latent Infections of Mouse and Man

Implications for Dementia

  • Chapter
Psychiatry and Biological Factors

Abstract

Latent herpesvirus infections are generally described to have three stages: establishment, maintenance, and reactivation. Since 1929 when Goodpasture postulated that latent herpesvirus infections are established in the nervous system, we have known the sites where latent infections are established but the events by which latent infections are established, maintained, and reactivated remain a mystery. To completely understand the latency phenomena of herpesviruses, we must understand not only the role of the virus during the latent infection, but also the contribution of the infected cell or tissue to this process.

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Author information

Authors and Affiliations

  1. Department of Microbiology, Mount Sinai School of Medicine, New York, New York, 10029, USA

    Anne M. Deatly

  2. Department of Microbiology, University of Minnesota, Minneapolis, Minnesota, 55455, USA

    Ashley T. Haase

  3. Department of Pathology, Clinical Neurological Sciences, and Psychiatry, University of Western Ontario, London, Ontario, N6A 5C1, Canada

    Melvyn J. Ball

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  1. Anne M. Deatly
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  2. Ashley T. Haase
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  3. Melvyn J. Ball
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Editors and Affiliations

  1. Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada

    Edouard Kurstak

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© 1991 Plenum Publishing Corporation

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Deatly, A.M., Haase, A.T., Ball, M.J. (1991). Herpes Simplex Virus Type 1 Transcription during Latent Infections of Mouse and Man. In: Kurstak, E. (eds) Psychiatry and Biological Factors. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5811-4_25

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  • DOI: https://doi.org/10.1007/978-1-4684-5811-4_25

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5813-8

  • Online ISBN: 978-1-4684-5811-4

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