Nutritional and Hemodynamic Factors Influencing Adenopituitary Function in Man

  • M. Vigaš
  • P. Tartár
  • D. Ježová
  • J. Jurčovičová
  • R. Kvetňanský
  • J. Malatinsky
  • R. Tigranyan
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 274)


Hypothalamic-pituitary functions are characterized by great variations in their activity. These include not only regular programmed alternations according to biological rhythms (lunar, circadian, ultradian, as well as the sleep-wake cycle) but also irregular ones induced by the given requirements for maintaining the steady state in different physiological situations.


Growth Hormone Mean Arterial Pressure Growth Hormone Secretion Lower Body Negative Pressure Plasma Growth Hormone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Ježová, D., R. Kvetanský, K. Kovacs, Z. Opršalová, M. Vigaš, and G.B. Makara, Insulin induced hypoglycemia activates the release of a adrenocorticotropin predominantly via central and propranolol insensitive mechanism, Endocrinology 120: 409–415, 1987.PubMedCrossRefGoogle Scholar
  2. 2.
    Heyrovský, A., Kolorimetriké stanoveni fruktosy kyselinou indolyloctovou, Chemicke listy 50: 1593–1597, 1956.Google Scholar
  3. 3.
    Schollberg, K., W. Jaross, E. Seker, A. Haschke, W. Wilke, G. Schmidt, R. Hentschel, B. Assmus, and G. Schirmer, Pituitary and adrenal hormones in patients after myocardial infarction under ergometric load, Atherosclerosis 49: 163–170, 1983.PubMedCrossRefGoogle Scholar
  4. 4.
    Daughaday, W.H., The anterior pituitary gland, In J.D. Wilson and D.W. Foster (eds) William’s Textbook of Endocrinology ,W.B. Saunders, Philadelphia, pp. 568–613, 1985.Google Scholar
  5. 5.
    Casanueva, F., L. Villanueva, A. Penalva, T. Vila, and J. Cabezas-Cerrato, Free fatty acid inhibition of exercise-induced growth hormone secretion, Horm Metab Res 13: 348–350, 1981.PubMedCrossRefGoogle Scholar
  6. 6.
    Casanueva, F.F., L. Villanueva, C. Dieguez, Y. Diaz, J.A. Cabranes, B. Szoke, M.F. Scanion, A.V. Schally, and A. Fernandez-Cruz, Free fatty acid block growth hormone (GH) releasing hormone-stimulated GH secretion in man directly at the pituitary, J Clin Endocrinol Metab 65: 634–642, 1987.PubMedCrossRefGoogle Scholar
  7. 7.
    Merimee, TJ., Familial Combined hyperlipoproteinemia. Evidence for a role of growth hormone deficiency in effecting its manifestation, J Clin Invest 65: 829–835, 1980.PubMedCrossRefGoogle Scholar
  8. 8.
    Collu, R., Neuroendocrine control of pituitary hormone secretion, In R. Collu (ed) Pediatric Endocrinology ,Raven Press, New York, pp. 1–36,1989.Google Scholar
  9. 9.
    Tuomisto, J., and P. Männistä, Neurotransmitter regulation of anterior pituitary hormones, Pharmacol Rev 37: 249–332, 1985.PubMedGoogle Scholar
  10. 10.
    Pardridge, W.M., Regulation of amino acid availability to the brain, In R.J. Wurtman and J.J. Wurtman (eds) Nutrition and the Brain ,Raven Press, New York, pp. 141–204, 1977.Google Scholar
  11. 11.
    Ježová-Repceková, D., M. Vigaš, and I. Klimeš, Decreased plasma Cortisol response to pharmacological stimuli after glucose load in man, Endocrinol Exper 14: 113–120, 1980.Google Scholar
  12. 12.
    Vigaš, M., Neuroendocrine reaction of man in stress, Veda, Bratislava, 1985 (in Slovak).Google Scholar
  13. 13.
    Hunter, W.M., C.C. Fonseka, and R. Passmore, The rôle of growth hormone in the mobilization of fuel for muscular exercise, Quart J Exper Physiol 50: 406–416, 1965.Google Scholar
  14. 14.
    Vigaš, M., J. Malatinský, S. Németh, and . Juroviová, Alpha-adrenergic control of growth hormone release during surgical stress in man, Metabolism Clin Exper 26: 399–402, 1977.CrossRefGoogle Scholar
  15. 15.
    Mims, R.B., C.L. Scott, O.M. Modebe, and J.E. Bethune, Prevention of L-dopa-induced growth hormone stimulation by hyperglycemia, J Clin Endocrinol Metab 37: 660–663, 1973.PubMedCrossRefGoogle Scholar
  16. 16.
    Ettigi, P., S. Lal, J.B. Martin, and H.G. Friesen, Effect of sex, oral contraception, and glucose loading on apomorphine-induced growth hormone secretion, J Clin Endocrinol Metab 40: 1094–1098, 1975.PubMedCrossRefGoogle Scholar
  17. 17.
    Nazar, K., Adrenocortical activation during long-term exercise in dogs: evidence for a glucostatic mechanism, Pflug Arch 329: 156–166, 1971.CrossRefGoogle Scholar
  18. 18.
    Galbo, H., N.J. Christensen, and J J. Holst, Glucose induced decrease in glucagon epinephrine responses to exercise in men, J Appl Physiol 42: 525–530, 1977.PubMedGoogle Scholar
  19. 19.
    Galbo, H., Hormonal and metabolic adaptation to exercise, George Thieme Verlag, Stuttgart, 1983.Google Scholar
  20. 20.
    Oldendorf, W.H., Brain uptake of radiolabeled amino acids, amines and hexoses after arterial injection, Am J Physiol 221: 1629–1639, 1971.PubMedGoogle Scholar
  21. 21.
    Masuda, A., T. Shibajaki, M. Nakahara, T. Imaki, Y. Kiosawa, K. Jibiki, H. Demura, K. Shizume, and N. Ling, The effect of glucose on growth hormone (GH) -releasing hormone -mediated GH secretion in man, J Clin Endocrinol Metab 60: 523–526, 1985.PubMedCrossRefGoogle Scholar
  22. 22.
    Oomura, Y., and H. Yoshimatsu, Neural network of glucose monitoring system, J Auto Nervous Sys 10: 359–372, 1984.CrossRefGoogle Scholar
  23. 23.
    Himsworth, R.L., P.W. Carmel, and A.G. Frantz, The location of the chemoreceptor controlling growth hormone secretion during hypoglycemia in primates, Endocrinology 91: 217–226, 1972.PubMedCrossRefGoogle Scholar
  24. 24.
    Aizawa, T., N.N. Yasuda, and M.A. Greer, Hypoglycemia stimulates ACTH secretion through a direct effect on the basal hypothalamus, Metabolism 30: 996–1000, 1981.PubMedCrossRefGoogle Scholar
  25. 25.
    Cane, P., R. Artal, and R.N. Bergman, Putative hypothalamic glucoreceptors play no essential role in the response to moderate hypoglycemia, Diabetes 35: 268–277, 1986.PubMedCrossRefGoogle Scholar
  26. 26.
    Sokolof, L., G.G. Fitzgerald, and E.E. Kaufman, Cerebral nutrition and energy metabolism, In R.J. Wurtman and J.J. Wurtman (eds) Nutrition and the Brain, Volume 1 ,Raven Press, New York, pp. 87–139, 1977.Google Scholar
  27. 27.
    Siesjö, B.K., Brain Energy Metabolism ,John Willey and Sons, Chichester, pp. 453–526, 1978.Google Scholar
  28. 28.
    Kovach, A.G.B., and P. Sandor, Cerebral Blood flow and brain function during hypotension and shock, Ann Rev Physiol 38: 571–596, 1976.CrossRefGoogle Scholar
  29. 29.
    Mills, D.E., and D. Robertshaw, Plasma prolactin responses to acute changes in central blood volume in man, Horm Res 18: 153–159, 1983.PubMedCrossRefGoogle Scholar
  30. 30.
    Kellerová, E., and M. Vigaš, Cerebral hypoperfusion as a stimulus for growth hormone release in man, Horm Res 12: 260–265, 1980.PubMedCrossRefGoogle Scholar
  31. 31.
    Vigaš, M., E. Martino, M. Bukovská, and P. Langer, Effect of acute cold exposure and insulin hypoglycemia on plasma thyrotropin levels by IRMA in healthy young males, Endocrinol Exper 22: 229–234, 1988.Google Scholar
  32. 32.
    Taylor, K.M., J.V. Jones, and M.S. Walker The Cortisol response during heart-lung bypass, Circulation 54: 20–25, 1976.PubMedGoogle Scholar
  33. 33.
    Malatinský, J., M. Vigaš, D. Vršanký, R. Kvetanský, . Jurovová, and D. Ježová, In vitro study of hormone degradation by heart-lung machine with bubble oxygenator, Resuscitation 11: 69–77, 1984.PubMedCrossRefGoogle Scholar
  34. 34.
    Yakota, H., Y. Kawashima, S. Hashimoto, H. Manabe, T. Onishi, T. Aono, and K. Matsumoto, Plasma Cortisol, luteinizing hormone (LH), and prolactin secretory response to cardiopulmonary bypass, J Surg Res 23: 196–200, 1977.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • M. Vigaš
    • 1
  • P. Tartár
    • 1
  • D. Ježová
    • 1
  • J. Jurčovičová
    • 1
  • R. Kvetňanský
    • 1
  • J. Malatinsky
    • 1
  • R. Tigranyan
    • 1
  1. 1.Institute of Experimental Endocrinology, Centre of Physiological SciencesSlovak Academy of SciencesBratislavaCzechoslovakia

Personalised recommendations