The Physiology of the Blood-Brain Barrier

  • Barbro B. Johansson
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 274)


A strict regulation of the neuronal environment is essential for optimal brain function. The blood-brain barrier (BBB), a concept including the morphological and functional mechanisms that restricts or facilitates the passage of substances from blood to brain, enables the brain environment to be regulated relatively independently of fluctuations in plasma concentrations. Although disagreement prevails regarding some specific mechanisms, our knowledge of the BBB physiology has advanced impressively during the last decades (1–13).


Brain Endothelial Cell Lipid Solubility Monocarboxylic Acid Brain Capillary Endothelial Cell Circumventricular Organ 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Barbro B. Johansson
    • 1
  1. 1.Department of NeurologyLund UniversityLundSweden

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