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Kindling 4 pp 93–112Cite as

Forebrain and Brainstem Mechanisms Governing Kindled Seizure Development: A Hypothesis

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Part of the book series: Advances in Behavioral Biology ((ABBI,volume 37))

Abstract

What is the nature of the kindling process? “Kindling” was coined by Goddard and his colleagues [20] to describe an observed phenomenon — the progressively increasing seizure generalization seen with repeated, temporally spaced stimulations of certain brain structures. From this phenomenological point of view, kindling is well named, since it appears to be a self-perpetuating process which once started continues inexorably to completion.

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Author information

Authors and Affiliations

  1. Comprehensive Epilepsy Program, Department of Neurology, University of Rochester School of Medicine, Rochester, NY, 14642, USA

    James L. Burchfiel & Craig D. Applegate

Authors
  1. James L. Burchfiel
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  2. Craig D. Applegate
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Editor information

Editors and Affiliations

  1. Neurosciences and Neurology, University of British Columbia, Vancouver, British Columbia, Canada

    Juhn A. Wada

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© 1990 Plenum Press, New York

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Burchfiel, J.L., Applegate, C.D. (1990). Forebrain and Brainstem Mechanisms Governing Kindled Seizure Development: A Hypothesis. In: Wada, J.A. (eds) Kindling 4. Advances in Behavioral Biology, vol 37. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5796-4_8

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  • DOI: https://doi.org/10.1007/978-1-4684-5796-4_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5798-8

  • Online ISBN: 978-1-4684-5796-4

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