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Kindling 4 pp 127–139Cite as

The GABA Hypothesis of Kindling

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Part of the book series: Advances in Behavioral Biology ((ABBI,volume 37))

Abstract

The GABA hypothesis, as recently revised (6), may be stated as follows:

“The kindling procedure causes a permanent change in some part of the GABA-A inhibitory system. This leads to a chronic tendency toward GABAergic hypofunction, and to all (or part) of the physiological abnormalities which characterize the ‘kindled state’.”

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Authors and Affiliations

  1. Department of Pharmacology, University of Toronto, Toronto, Ontario, M5S 1A8, USA

    W. McIntyre Burnham & Georgia A. Cottrell

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  1. W. McIntyre Burnham
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  2. Georgia A. Cottrell
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Editors and Affiliations

  1. Neurosciences and Neurology, University of British Columbia, Vancouver, British Columbia, Canada

    Juhn A. Wada

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© 1990 Plenum Press, New York

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McIntyre Burnham, W., Cottrell, G.A. (1990). The GABA Hypothesis of Kindling. In: Wada, J.A. (eds) Kindling 4. Advances in Behavioral Biology, vol 37. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5796-4_10

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  • DOI: https://doi.org/10.1007/978-1-4684-5796-4_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5798-8

  • Online ISBN: 978-1-4684-5796-4

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