Abstract
Even though it is difficult to determine the first time heat or a hot instrument was used for treatment of malignant tumors, by the year 2000 B.C., the use of cauterization for treatment of tumors was one of the methods of therapy. Hippocrates also was aware of the effect of fever in treatment of infectious disease, as well as malignant tumors, but it was not until the second half of the 1800s that we have documented evidence of resolution of sarcomas by hyperthermia. In 1866, Bush reported several papers in medical literature claiming the relationship on disappearance of malignant tumors. This, followed by Coley’s innovative work in 1893, published in The American Journal of Medical Science, showed impressive results of fever on malignant tumors.
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© 1990 Plenum Press, New York
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Shidnia, H. (1990). Consensus of Hyperthermia for the 1990s. In: Bicher, H.I., McLaren, J.R., Pigliucci, G.M. (eds) Consensus on Hyperthermia for the 1990s. Advances in Experimental Medicine and Biology, vol 267. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5766-7_4
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DOI: https://doi.org/10.1007/978-1-4684-5766-7_4
Publisher Name: Springer, Boston, MA
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