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Parvalbumin, Molecular and Functional Aspects

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Calcium Binding Proteins in Normal and Transformed Cells

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 269))

Abstract

Parvalbumin was the first calcium-binding protein to be crystallized (Kretsinger 1980). From these data, the EF-hand structural arrangement, common to many calcium-binding proteins, was deduced. Parvalbumin contains 3 EF-hands but only the two COOH-terminal domains bind calcium. Parvalbumins were first isolated from the skeletal muscle of lower vertebrates (Hamoir, 1968; Pechère et al., 1971; Gerday, 1988) and later from skeletal muscles, testis, kidney and brain of various species including man (Heizmann, 1984; Heizmann and Berchtold, 1987).

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Author information

Authors and Affiliations

  1. Department of Pediatrics, Division of Clinical Chemistry, University of Zürich, Steinwiesstrasse 75, 8032, Zürich, Switzerland

    Claus W. Heizmann

  2. Max-Planck Institute for Brain Research, D-6000, Frankfurt 71, Germany

    Jürg Röhrenbeck

  3. Department of General Zoology, University of Amsterdam, Amsterdam, The Netherlands

    Willem Kamphuis

Authors
  1. Claus W. Heizmann
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  2. Jürg Röhrenbeck
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  3. Willem Kamphuis
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Editor information

Editors and Affiliations

  1. Laboratoire d’Histologie Faculté de Médecine, Free University of Brussels, 2 rue Evers, 1000, Brussels, Belgium

    Roland Pochet

  2. AFRC Institute of Animal Physiology and Genetics Research, Babraham Hall, Cambridge, CB2 4AT, UK

    D. Eric M. Lawson

  3. Division of Clinical Chemistry, Department of Pediatrics, University of Zurich, Sternwiesstraße 75, CH-8032, Zurich, Switzerland

    Claus W. Heizmann

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© 1990 Plenum Press, New York

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Heizmann, C.W., Röhrenbeck, J., Kamphuis, W. (1990). Parvalbumin, Molecular and Functional Aspects. In: Pochet, R., Lawson, D.E.M., Heizmann, C.W. (eds) Calcium Binding Proteins in Normal and Transformed Cells. Advances in Experimental Medicine and Biology, vol 269. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5754-4_8

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  • DOI: https://doi.org/10.1007/978-1-4684-5754-4_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5756-8

  • Online ISBN: 978-1-4684-5754-4

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