Abstract
Secretion of many neurotransmitters, hormones and enzymes has long been known to require extracellular calcium (Douglas 1968; Katz 1969) and this fact was important in formulating the idea that a rise in intracellular calcium is the trigger for secretion. Additional data corroborating the role of calcium in secretion were obtained from measurements of calcium influx associated with secretion and in triggering secretion by introducing calcium directly into the cytosol. To date, the role of calcium as the triggering and controlling agent in the secretory process has been firmly established, but the question of what this role entails still awaits elucidation.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Artalejo C.R., Bader M.F., Aunis D., and Garcia A.G., 1986. Biochim. Biophys. Res. Commun., 134, 1–7.
Artalejo C.R., Garcia A.G., and Aunis D., 1987. J. Biol. Chem., 262, 915–926.
Bader M.F., Thiersé D., Aunis D., Ahnert-Hilger G., and Gratzl M., 1986a, J. Biol. Chem., 261, 5777–5783.
Bader M.F., Trifaro J.M., Langley K.O., Thiersé D., and Aunis D., 1986b. J. Cell Biol. 102, 636–646.
Bernstein B.W., and Bamburg J.R., 1987. Neurochem. Res., 12, 929–935.
Burgoyne R.D., Cheek T.R., and Norman K.M., 1986. Nature. 319, 68–70.
Cheek T.R., and Burgoyne R.D., 1986. FEBS Lett., 207, 110–114.
Douglas W.W., 1968. Br. J. Pharmacol. 34, 451–474.
Gomperts B.D., and Fernandez J.M., 1985. Trends Biochem. Sci., 10, 414–417.
Grant N.J., Aunis D., and Bader M.F., 1987. Neuroscience. 23, 1143–1155.
Haycock J.W., Megileni J.A., Bennett W.F., and Waymire J.C., 1982. J. Biol. Chem., 257, 12641–12648.
Kao L.S., and Schneider A.S., 1986. J. Biol Chem., 261, 4881–4888.
Katz B., 1969, “The Release of Neurotransmitter Substances”, Liverpool University Press, Liverpool
Kenigsberg R.L., and Trifaro J.M., 1980. Neuroscience. 5, 1547–1556.
Langley O.K., Perrin D., and Aunis D., 1986. J. Histochem. Cvtochem., 34, 517–525.
Meligeni J.A., Haycock J.W., Bennett W.F., and Waymire J.C., 1982. J. Biol Chem., 257, 12632–12640.
Perrin D., Langley O.K., and Aunis D., 1987. Nature. 326, 498–501.
Pfeiffer J.R., Seagrave J.C., Davis B.H., Deanin G.G., and Oliver J.M., 1985. J. Cell Biol. 101, 2145–2155.
Sarafian T., Aunis D., and Bader M.F., 1987. J. Biol. Chem., 262, 16671–16676.
Simon J.P., Bader M.F., and Aunis D., 1988. Proc. Natl Acad. Sci.USA. 85, 1712–1716.
Simon J.P., Bader M.F., and Aunis D., 1989. Biochem. J., 260, 915–922.
Sontag J.M., Aunis D., and Bader M.F., 1988. Eur. J. Cell Biol. 46, 316–326.
Waschek J.A., Pruss R.M. Siegel R.E., Eiden L.E., Bader M.F., and Aunis D., 1987. Ann. N.Y. Acad. Sci., 493, 308–323.
Wulf E., Deroben A., Bautz F.A., Faulstich H., and Whieland T., 1979. Proc. Natl. Acad. Sci. USA. 76. 4498–4502.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Plenum Press, New York
About this chapter
Cite this chapter
Bader, MF., Simon, JP., Sontag, JM., Langley, K., Aunis, D. (1990). Role of Calcium in Secretion and Synthesis in Bovine Adrenal Chromaffin Cells. In: Pochet, R., Lawson, D.E.M., Heizmann, C.W. (eds) Calcium Binding Proteins in Normal and Transformed Cells. Advances in Experimental Medicine and Biology, vol 269. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5754-4_14
Download citation
DOI: https://doi.org/10.1007/978-1-4684-5754-4_14
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-5756-8
Online ISBN: 978-1-4684-5754-4
eBook Packages: Springer Book Archive