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Transduction in Biological Systems pp 75–85Cite as

A Complex Regulation of the cGMP-Dependent Channels of Retinal Rod Membranes by the cGMP Phosphodiesterase

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Abstract

Photoexcitation induces a hyperpolarization of the plasma membrane of the rod outer segment, and it is now clearly established that this hyperpolarization results from a decrease of cGMP* concentration which directly regulates the opening of sodium channels of this membrane (see Haynes and Yau, Chapter 3 in this volume, and Hanke and Simmoteit, Chapter 4 in this volume; for a review, see Pugh and Cobbs(1)). cGMP-dependent sodium channels are also present in the membranes of the disks.(2–7)

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References

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Authors and Affiliations

  1. Laboratoire Biophysique Moléculaire et Cellulaire, Centre d’Etudes Nucléaires de Grenoble, 38041, Grenoble Cedex, France

    Michele Ildefonse, Nelly Bennett, Serge Crouzy, Yves Chapron & Armel Clerc

Authors
  1. Michele Ildefonse
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  2. Nelly Bennett
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  3. Serge Crouzy
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  4. Yves Chapron
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  5. Armel Clerc
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Editor information

Editors and Affiliations

  1. Centro de Estudios Científicos de Santiago, Universidad de Chile, Santiago, Chile

    Cecilia Hidalgo  & Enrique Jaimovich  & 

  2. Universidad de Chile, Santiago, Chile

    Juan Bacigalupo

  3. University of California at Los Angeles, Los Angeles, California, USA

    Julio Vergara

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© 1990 Plenum Press, New York

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Ildefonse, M., Bennett, N., Crouzy, S., Chapron, Y., Clerc, A. (1990). A Complex Regulation of the cGMP-Dependent Channels of Retinal Rod Membranes by the cGMP Phosphodiesterase. In: Hidalgo, C., Bacigalupo, J., Jaimovich, E., Vergara, J. (eds) Transduction in Biological Systems. Series of the Centro de Estudios Científicos de Santiago. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5736-0_6

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  • DOI: https://doi.org/10.1007/978-1-4684-5736-0_6

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5738-4

  • Online ISBN: 978-1-4684-5736-0

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