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Role of Slow Inward Calcium Current in Excitation-Contraction Coupling

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Transduction in Biological Systems

Abstract

The role of external calcium in the process of excitation-contraction coupling of skeletal muscle fibers had been investigated extensively. Removal of external calcium has been shown to not prevent the contractile activation, but it does have distinct effects on contracture amplitude and duration and on the voltage-dependence of contractile inactivation.(1–5) Furthermore, it has been demonstrated recently that the magnitude and time course of myoplasmic calcium transients elicited by membrane depolarization depend strongly on extracellular calcium.(6)

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Authors and Affiliations

  1. Laboratoire de Physiologie des Elements Excitables, Université Claude Bernard, F-69622, Villeurbanne Cedex, France

    Vincent Jacquemond & Oger Rougier

Authors
  1. Vincent Jacquemond
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  2. Oger Rougier
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Editors and Affiliations

  1. Centro de Estudios Científicos de Santiago, Universidad de Chile, Santiago, Chile

    Cecilia Hidalgo  & Enrique Jaimovich  & 

  2. Universidad de Chile, Santiago, Chile

    Juan Bacigalupo

  3. University of California at Los Angeles, Los Angeles, California, USA

    Julio Vergara

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© 1990 Plenum Press, New York

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Jacquemond, V., Rougier, O. (1990). Role of Slow Inward Calcium Current in Excitation-Contraction Coupling. In: Hidalgo, C., Bacigalupo, J., Jaimovich, E., Vergara, J. (eds) Transduction in Biological Systems. Series of the Centro de Estudios Científicos de Santiago. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5736-0_22

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  • DOI: https://doi.org/10.1007/978-1-4684-5736-0_22

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5738-4

  • Online ISBN: 978-1-4684-5736-0

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