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Synexin-Driven Membrane Fusion: Molecular Basis for Exocytosis

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Transduction in Biological Systems

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Abstract

Secretion by exocytosis involves fusion of a secretory vesicle membrane with the plasma membrane of the secreting cell. In many endocrine cells, including chromaffin cells and pancreatic β-cells, such simple exocytosis is followed by contact and fusion of more deeply situated secretory vesicles with the initially fused secretory vesicle membranes. The latter process is called compound exocytosis, and presumably allows for additional secretion without moving secretory granules long distances through the cytoskeleton to reach the plasma membrane.

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Authors and Affiliations

  1. Laboratory of Cell Biology and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, 20892, USA

    Eduardo Rojas, A. Lee Burns & Harvey B. Pollard

Authors
  1. Eduardo Rojas
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  2. A. Lee Burns
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  3. Harvey B. Pollard
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Editors and Affiliations

  1. Centro de Estudios Científicos de Santiago, Universidad de Chile, Santiago, Chile

    Cecilia Hidalgo  & Enrique Jaimovich  & 

  2. Universidad de Chile, Santiago, Chile

    Juan Bacigalupo

  3. University of California at Los Angeles, Los Angeles, California, USA

    Julio Vergara

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© 1990 Plenum Press, New York

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Rojas, E., Burns, A.L., Pollard, H.B. (1990). Synexin-Driven Membrane Fusion: Molecular Basis for Exocytosis. In: Hidalgo, C., Bacigalupo, J., Jaimovich, E., Vergara, J. (eds) Transduction in Biological Systems. Series of the Centro de Estudios Científicos de Santiago. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5736-0_12

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  • DOI: https://doi.org/10.1007/978-1-4684-5736-0_12

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