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Biological Activities and Clinical Potential of Ebselen

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Antioxidants in Therapy and Preventive Medicine

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 264))

Abstract

Ebselen (2-pheny1–1,2-benzisoselenazol-3(2H)-one; Fig. 1) is a seleno-organic compound which exhibits catalytic GSH-dependent, hydroperoxide reducing properties, similar to the action of glutathione peroxidase (GSH-Px)1–3.

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Author information

Authors and Affiliations

  1. Cologne Research Centre, Rhône-Poulenc/Nattermann, P.O. Box 350120, D-5000, Cologne 30, Germany

    Michael J. Parnham

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  1. Michael J. Parnham
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Editor information

Editors and Affiliations

  1. Centre National de la Recherche Scientifique, University of Paris, Paris, France

    Ingrid Emerit

  2. Dept. of Physiology Anatomy, University of California, Berkeley, Berkeley, California, 94720, USA

    Lester Packer

  3. Institut Gustave-Roussy, 94800, Villejuif, France

    Christian Auclair

  4. Groupe de Recherche Radicaux Libres, Institut Biomédical des Cordeliers, 15, Rue de l’Ecole de Médecine, 75006, Paris, France

    Ingrid Emerit

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© 1990 Plenum Press, New York

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Parnham, M.J. (1990). Biological Activities and Clinical Potential of Ebselen. In: Emerit, I., Packer, L., Auclair, C. (eds) Antioxidants in Therapy and Preventive Medicine. Advances in Experimental Medicine and Biology, vol 264. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5730-8_31

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  • DOI: https://doi.org/10.1007/978-1-4684-5730-8_31

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5732-2

  • Online ISBN: 978-1-4684-5730-8

  • eBook Packages: Springer Book Archive

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