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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 260))

Abstract

Anemia is a common feature in patients with chronic renal failure on regular dialysis treatment. The inappropriate low level of serum erythropoietin is known to be the major cause of anemia in these patients1. The development of recombinant human erythropoietin (rHuEPO) offers for the first time the possibility of an effective and continuous correction of renal anemia2 , 3 . In recent publications several authors described an increase of hematocrit in patients undergoing regular hemodialysis during treatment with rHuEPO2–7. In the initial trials rHuEPO treatment was associated with various adverse effects such as hypertension, convulsions, fistula clotting, and increased serum creatinine, urea, and potassium 2–4.

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© 1989 Plenum Press, New York

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Steinhauer, H.B. (1989). Effects of Long-Term Treatment with Human Recombinant Erythropoietin in Patients on CAPD. In: Hörl, W.H., Schollmeyer, P.J. (eds) New Perspectives in Hemodialysis, Peritoneal Dialysis, Arteriovenous Hemofiltration, and Plasmapheresis. Advances in Experimental Medicine and Biology, vol 260. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5718-6_17

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  • DOI: https://doi.org/10.1007/978-1-4684-5718-6_17

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5720-9

  • Online ISBN: 978-1-4684-5718-6

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