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The Immune Response to Viral Infections pp 205–209Cite as

Delta Virus Hepatitis

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 257))

Abstract

The Hepatitis Delta Virus (HVD) occupies a unique niche in humai virology. At variance with conventional animal viruses, it cannot replicate autonomously but requires the presence of the Hepatitis B Virus (HBV) to initiate infection. It behaves like a defective interfering agent, in that it ihibits the synthesis of the competent HBV helper once its infection is established. This cooperation is reflected in the HD virion, a 36 nm spherical particle formed by an envelope of HBV-derived surface antigen (HBsAg), which encloses the genome and a specific delta antigen (HD-Ag) (1).

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Author information

Authors and Affiliations

  1. Divisione di Gastroenterologia, Molinette, Cs. Bramante 88, Torino, Italy

    Mario Rizzetto

Authors
  1. Mario Rizzetto
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Editor information

Editors and Affiliations

  1. National Institute for Medical Research, London, UK

    B. A. Askonas

  2. National Institutes of Health, Bethesda, Maryland, USA

    B. Moss

  3. World Health Organization, Geneva, Switzerland

    G. Torrigiani

  4. Fondazione Internazionale Menarini, Florence, Italy

    S. Gorini

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© 1989 Plenum Press, New York

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Rizzetto, M. (1989). Delta Virus Hepatitis. In: Askonas, B.A., Moss, B., Torrigiani, G., Gorini, S. (eds) The Immune Response to Viral Infections. Advances in Experimental Medicine and Biology, vol 257. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5712-4_19

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  • DOI: https://doi.org/10.1007/978-1-4684-5712-4_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5714-8

  • Online ISBN: 978-1-4684-5712-4

  • eBook Packages: Springer Book Archive

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