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Disorders of the Anal Sphincters

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Pathogenesis of Functional Bowel Disease

Part of the book series: Topics in Gastroenterology ((TGEN))

Abstract

The anal sphincter is really two sphincters in one. It consists of an inner ring of smooth muscle, which is contiguous with the smooth muscle of the rectum, and an outer striated muscle ring, which is linked functionally to the puborectalis fibers of the levator ani complex (Fig. 1). The internal sphincter (IAS) is not under conscious control, but like all other smooth muscle sphincters, relaxes when the bowel immediately proximal to it contracts or is distended. The external sphincter (EAS) and puborectalis are under conscious control and tend to contract together, increasing the sphincter resistance and accentuating the anorectal angulation.

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References

  1. Bouvier M, Gonnella J: Nervous control of the internal anal sphincter of the cat. J Physiol (London) 310: 457–469, 1981

    CAS  Google Scholar 

  2. Rayner V: Characteristic of the internal anal sphincter and the rectum of the vervet monkey. J Physiol (London) 286: 383–399, 1979

    CAS  Google Scholar 

  3. Burleigh DE, D’Mello A: Physiology and pharmacology of the internal anal sphincter, in Henry MM, Swash M (eds): Coloproctology and the Pelvic Floor: Pathophysiology and Management. London, Butter-worths, 1985, pp 22–41

    Google Scholar 

  4. Gonella J, Bouvier M, Blanquet F: The external innervation of motility of the small and large intestines and related sphincters. Physiol Rev 67: 902–961, 1987

    PubMed  CAS  Google Scholar 

  5. Shepherd JJ, Wright PG: The response of the internal anal sphincter in man to stimulation of the presacral nerve. Am J Dig Dis 13: 421–427, 1968

    Article  PubMed  CAS  Google Scholar 

  6. Gibbons CP, Bannister JJ, Trowbridge EA, et al: An analysis of anal sphincter pressure and anal compliance in normal subjects. Int J Colorect Dis 1: 231–237, 1986

    Article  CAS  Google Scholar 

  7. Gibbons CP, Trowbridge EA, Bannister JJ, et al: The mechanics of the anal sphincter complex. J Biomech 21: 601–604, 1988

    Article  PubMed  CAS  Google Scholar 

  8. Read MG, Read NW. Haynes WG, et al: A prospective study of the effect of haemorrhoids on sphincter function and faecal continence. Br J Surg 69:396–398, 1982

    Article  PubMed  CAS  Google Scholar 

  9. Whitehead WE, On WC, Engel BT, et al: External anal sphincter response to rectal distension: Learned response or reflex? Psychophysiology 19: 57–72, 1982

    Article  PubMed  CAS  Google Scholar 

  10. Duthie HL, Bennett RC: The relation of sensation in the anal canal to the functional anal sphincter; a possible factor in anal continence. Gut 4: 179–182, 1963

    Article  PubMed  CAS  Google Scholar 

  11. Swash M: Histopathology of the pelvic floor muscles, in Henry MM, Swash M (eds): Coloproctology and the Pelvic Floor. London Butterworths, 1985, pp 138–143

    Google Scholar 

  12. Salducci J, Planche D, Naudy B: Physiological role of the internal anal sphincter and the external anal sphincter during micturition, in Weinbeck M (ed): Motility of the Digestive Tract. New York, Raven Press, 1982, pp 513–520

    Google Scholar 

  13. Sun WM, Donnelly TC, Read NW: Anorectal function in normal subjects: Effect of gender. Gastroenterology 94: A449, 1988

    Google Scholar 

  14. Monges HO, Salducci J, Naudy B, et al: The electrical activity of the internal anal sphincter: A comparative study in man and in cats, in Christensen L (ed): Gastrointestinal Motility. New York, Raven Press, 1980, pp 495–501

    Google Scholar 

  15. Henry MM, Parks AG, Swash M: The pelvic floor musculature in the descending perineum syndrome. Br J Surg 69: 470–472, 1982

    Article  PubMed  CAS  Google Scholar 

  16. Read NW, Bannister JJ: Anorectal manometry: Techniques in health and anorectal disease, in Henry MM, Swash M (eds): Coloproctology and the Pelvic Floor. London, Butterworths, 1985, pp 65–87

    Google Scholar 

  17. Bartolo DCC, Jarratt JA, Read NW: The use of conventional EMG to assess external sphincter neuropathy in man. J Neurol Neurosurg Psychiatry 46: 1115–1118, 1983

    Article  PubMed  CAS  Google Scholar 

  18. Kiff ES, Swash M: Slowed conduction in the pudendal nerves in idiopathic (neurogenic) faecal incontinence. Br J Surg 71: 614–616, 1984

    Article  PubMed  CAS  Google Scholar 

  19. Snooks SJ, Swash M, Setchell M, et al: Injury to innervation of pelvic floor sphincter musculature in childbirth. Lancet 2: 546–550, 1984

    Article  PubMed  CAS  Google Scholar 

  20. Bartolo DCC, Read NW, Jarratt JA, et al: The role of partial denervation of the puborectalis in idiopathic faecal incontinence. Br J Surg 70: 664–667, 1983

    Article  PubMed  CAS  Google Scholar 

  21. Read NW, Bartolo DCC, Read MG: Differences in anal function in patients with incontinence to solids and in patients with incontinence to liquids. Br J Surg 71: 39–42, 1984

    Article  PubMed  CAS  Google Scholar 

  22. Schuster MM: The riddle of the sphincters. Gastroenterology 69: 249–262, 1979

    Google Scholar 

  23. Parks AG: Anorectal incontinence. Proc R Soc Med 68: 681–690, 1975

    PubMed  CAS  Google Scholar 

  24. Schiller LRA, Santa Ana CA, Schmulen AC, et al: Pathogenesis of faecal incontinence in diabetes mellitus. N Engl J Med 207: 1666–1671, 1982

    Article  Google Scholar 

  25. Sun WM, Donnelly TC, Read NW: Impaired internal sphincter function in patients with idiopathic faecal incontinence. Gastroenterology 94: A449, 1988

    Google Scholar 

  26. Aaronson I, Nixon HH: A clinical evaluation of anorectal pressure studies in the diagnosis of Hirschsprung’s disease. Gut 13: 138–146, 1972

    Article  PubMed  CAS  Google Scholar 

  27. Faverdom C, Dornic C, Ahran P: Quantitative analysis of anorectal pressures in Hirschsprung’s disease. Dis Colon Rectum 24: 422–427, 1981

    Article  Google Scholar 

  28. Meunier P, Marechal JM, Jaubert de Beaujeu M: Recto-anal pressures and rectal sensitivity in childhood constipation. Gastroenterology 77: 330–336, 1979

    PubMed  CAS  Google Scholar 

  29. Lennard-Jones JE: Constipation: Pathophysiology, clinical features and treatment, in Henry MM, Swash M (eds): Coloproctology and the Pelvic Floor: Pathophysiology and Management. London, Butterworths, 1985, pp 350–375

    Google Scholar 

  30. Baldi F, Ferrarini F, Corinadesi R, et al: Function of the internal anal sphincter and rectal sensitivity in idiopathic constipation. Digestion 24: 14–22, 1982

    Article  PubMed  CAS  Google Scholar 

  31. Frenckner B, Ihre T: Influence of autonomic nerves on the internal anal sphincter in man. Gut 17: 306–312, 1976

    Article  PubMed  CAS  Google Scholar 

  32. Dent J, Dodds WJ, Friedman RH, et al: Mechanism of gastroesophageal reflux in recumbent asymptomatic human subjects. J Clin Invest 65: 256–267, 1980

    Article  PubMed  CAS  Google Scholar 

  33. Dodds WJ, Dent J, Hogan JF, et al: Mechanism of gastroesophageal reflux in patients with reflux esophagitis. N Engl J Med 307: 1547–1552, 1982

    Article  PubMed  CAS  Google Scholar 

  34. Sun WM, Donnelly TC, Read, NW: Inappropriate transient anal relaxations: A cause of faecal incontinence? Gastroenterology 94: A449, 1988

    Google Scholar 

  35. Callaghan RP, Dixon HH: Megarectum: Physiological observation. Arch Dis Child 39: 153–157, 1984

    Article  Google Scholar 

  36. Denny-Brown D, Robertson EG: An investigation of the nervous control of defaecation. Brain 58: 256–310, 1935

    Article  Google Scholar 

  37. Meunier P, Mollard P: Control of the internal anal sphincter (manometric study with human subjects). Pflügers Arch 370: 233–239, 1977

    Article  PubMed  CAS  Google Scholar 

  38. Naudy B, Planche D, Monges B, et al: Relaxations of the internal anal sphincter elicited by rectal distension and extrarectal distension in man, in Roman C (ed): Gastrointestinal Motility. Lancaster, MTP Press, 1983, pp 451–458

    Google Scholar 

  39. Sun WM, Read NW: Anorectal manometry and rectal sensation in patients with the irritable bowel syndrome. Gastroenterology 94: A450, 1988

    Google Scholar 

  40. Rao SSC, Holdsworth CD, Read NW: Anorectal sensitivity and reactivity in patients with ulcerative colitis. Gastroenterology 93: 1270–1275, 1987

    PubMed  CAS  Google Scholar 

  41. Whitehead WE, Engel BT, Schuster MM: Irritable bowel syndrome. Dig Dis Sci 25: 404–413, 1980

    Article  PubMed  CAS  Google Scholar 

  42. Gonella J, Bouvier M, Blanquet F: Extrinsic nervous control of motility of small and large intestine and related sphincters. Physiol Rev 67: 903–961, 1987

    Google Scholar 

  43. Schiller LR, Santa Ana CA, Schmulen AC, et al: Pathogenesis of faecal incontinence in diabetes mellitus. N Engl J Med 307: 1666–1671, 1982

    Article  PubMed  CAS  Google Scholar 

  44. Sasaki H, Yoshida T, Noda K, et al: Urethral pressure profiles following radical hysterectomy. Obstet Gynecol 59: 101–104, 1982

    PubMed  CAS  Google Scholar 

  45. Wald A, Tunuguntla AK: Anorectal sensation dysfunction in faecal incontinence and diabetes mellitus. N Engl J Med 310: 1282–1287, 1984

    Article  PubMed  CAS  Google Scholar 

  46. Buser WD, Miner PB Jr: Delayed rectal sensation with faecal incontinence; successful treatment using anorectal manometry. Gastroenterology 91: 1186–1191, 1986

    PubMed  CAS  Google Scholar 

  47. Guttmann L: Spinal Cord Injuries. London, Blackwell, 1976

    Google Scholar 

  48. Melzak J, Porter NH: Studies of the reflex activity of the external sphincter ani in spinal man. Paraplegia 1: 277–296, 1964

    Article  PubMed  CAS  Google Scholar 

  49. Frenckner B: Function of the anal sphincters in spinal man. Gut 16: 638–644, 1975

    Article  PubMed  CAS  Google Scholar 

  50. Wheatley IC, Hardy KJ, Dent J: Anal pressure studies in spinal patients. Gut 18: 488–490, 1977

    Article  PubMed  CAS  Google Scholar 

  51. White JC, Verlot MG, Ehrentheil O: Neurogenic disturbances of the colon and their investigation by the colonmetrogram. Ann Surg 112: 1042–1056, 1940

    Article  PubMed  CAS  Google Scholar 

  52. Phillips SF, Edwards DAW: Some aspects of anal continence and defaecation. Gut 6: 396–405, 1965

    Article  PubMed  CAS  Google Scholar 

  53. Parks AG, Porter NH, Melzack J: Experimental study of the reflex mechanism controlling the muscles of the pelvic floor. Dis Colon Rectum 5: 507–414, 1962

    Article  Google Scholar 

  54. Finlay IG, Brown D: Posterior pelvic floor repair—A new surgical approach for outlet obstruction constipation (obstructed defaecation). Gut 29: A1546, 1988

    Google Scholar 

  55. Brown DC, Lauder JC, Poon FW, et al: Outlet obstruction constipation (obstructed defaecation)—a failure of the posterior pelvic floor? Gut 29: A734, 1988

    Google Scholar 

  56. Preston DM, Lennard-Jones JE: Severe chronic constipation of young women: Idiopathic slow transit constipation. Gut 27: 41–48, 1986

    Article  PubMed  CAS  Google Scholar 

  57. Read NW, Timms JM, Barfield LJ, et al: Impairment of defaecation in young women with severe constipation. Gastroenterology 90: 53–60, 1986

    PubMed  CAS  Google Scholar 

  58. Barnes PRH, Lennard-Jones JE: Balloon expulsion from the rectum in constipation of different types. Gut 25: 1049–1052, 1985

    Article  Google Scholar 

  59. Barnes PRH, Hawley PR, Preston DM, et al: Experience of posterior division of the puborectalis muscle in the management of chronic constipation. Br J Surg 72: 475–477, 1985

    Article  PubMed  CAS  Google Scholar 

  60. Smith B: Effect of irritant purgatives on the myenteric plexus in man and the mouse. Gut 9: 139–143, 1968

    Article  PubMed  CAS  Google Scholar 

  61. Kamm MA, Hawley PR, Lennard-Jones JE: Outcome of colectomy for severe idiopathic constipation. Gut 29: 969–973, 1988

    Article  PubMed  CAS  Google Scholar 

  62. Preston DM, Lennard-Jones JE: Pelvic colon motility and response to intraluminal bisacodyl in slow transit constipation. Dig Dis Sci 30: 289–294, 1985

    Article  PubMed  CAS  Google Scholar 

  63. Wood JD: Physiology of the enteric nervous system, in Johnson LR (ed): Physiology of the Gastrointestinal Tract, ed 2. New York, Raven Press, 1987, pp 67–109

    Google Scholar 

  64. Brocklehurst JC, Khan MY: A study of fecal stasis in old age and the use of Dorbanex in its prevention. Gerontol Clin 11: 293–300, 1969

    Article  CAS  Google Scholar 

  65. Banks S, Marks, IN: The aetiology, diagnosis and treatment of constipation and diarrhoea in geriatric patients. S Afr Med J 51: 509–414, 1977

    Google Scholar 

  66. Read NW, Abouzekry L, Read MG, et al: Anorectal function in elderly patients with faecal impaction. Gastroenterology 89: 959–966, 1985

    PubMed  CAS  Google Scholar 

  67. Read NW, Abouzekry L: Why do patients with faecal impaction have faecal incontinence? Gut 27: 283287, 1986

    Google Scholar 

  68. Gibbons CP, Bannister JJ, Read NW: Role of constipation and anal hypertonia in the pathogenesis of haemorrhoids. Br J Surg 75: 656–660, 1988

    Article  PubMed  CAS  Google Scholar 

  69. Sun WM, Donnelly TC, Read NW, et al: Is the high anal pressure in patients with haemorrhoids of vascular origin? Gastroenterology 94: A449, 1988

    Google Scholar 

  70. Thompson WHF: The nature of haemorrhoids. Br J Surg 62: 542–555, 1975

    Article  Google Scholar 

  71. Hancock BD: Internal sphincter and the nature of haemorrhoids. Gut 18: 651–6756, 1976

    Article  Google Scholar 

  72. Womack NR, Williams NS, Holmfield JHM, et al: Pressure and prolapse the cause of solitary rectal ulceration. Gut 28: 1228–1233, 1987

    Article  PubMed  CAS  Google Scholar 

  73. Bartolo DCC, Read NW, Jarratt JA, et al: Differences in anal sphincter function and clinical presentation in patients with pelvic floor descent. Gastroenterology 85: 68–75, 1983

    PubMed  CAS  Google Scholar 

  74. Sun WM, Read NW: Rectal prolapse, anterior mucosal prolapse, solitary rectal ulcer: Are they caused by rectal herniation through a weak sphincter? Gut 28: A1363, 1987

    Google Scholar 

  75. Mahieu P, Pringot J, Bodart P: Defaecography II. Contribution to the diagnosis of defaecation disorders. Gastrointest Radio 9: 253–261, 1984

    Article  CAS  Google Scholar 

  76. Manning AP, Thompson WG, Heaton KW, et al: Towards positive diagnosis of irritable bowel. Br Med J 2: 653–654, 1978

    Article  PubMed  CAS  Google Scholar 

  77. Bannister JJ, Davison P, Timms JM, et al: Effect of the stool size and consistency of defaecation. Gut 28: 1246–1250, 1987

    Article  PubMed  CAS  Google Scholar 

  78. Sullivan MA, Cohen S, Snape WJ: Colonic myoelectrical activity in the irritable bowel syndrome; effect of eating and anticholinergics. N Engl J Med 298: 878–883, 1978

    Article  PubMed  CAS  Google Scholar 

  79. Harvey RE, Read AE: Effect of cholecystokinin on colonic motility and symptoms in patients with irritable bowel syndrome. Lancet 1: 1–3, 1973

    Article  PubMed  CAS  Google Scholar 

  80. Taylor I, Basu P, Hammond P, et al: Effect of bile acid perfusion on colonic motor function in patients with irritable bowel syndrome. Gut 21: 843–847, 1980

    Article  PubMed  CAS  Google Scholar 

  81. Merrick MV, Eastwood MA, Ford MJ: Is bile and malabsorption under diagnosed? An evaluation of accuracy of diagnosis by measurement of Se HCAT retention. Br Med J 290: 665–668, 1985

    Article  CAS  Google Scholar 

  82. Cann A, Read NW, Brown C, et al: The irritable bowel syndrome (IBS) relationship of disorders in the transit of a single solid meal to symptom patterns. Gut 24: 405–411, 1983

    Article  PubMed  CAS  Google Scholar 

  83. Cann PA, Read NW, Holdsworth CD, et al: The role of loperamide and placebo in the management of the irritable bowel syndrome (IBS). Dig Dis Sci 29: 239–247, 1984

    Article  PubMed  CAS  Google Scholar 

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© 1989 Plenum Publishing Corporation

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Read, N.W., Sun, W.M. (1989). Disorders of the Anal Sphincters. In: Snape, W.J. (eds) Pathogenesis of Functional Bowel Disease. Topics in Gastroenterology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5694-3_14

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  • DOI: https://doi.org/10.1007/978-1-4684-5694-3_14

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