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Ovarian Tumors, Stem Cells and Ontogeny: Imminentes Cognitiones

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Book cover Growth Factors and the Ovary

Abstract

Two fundamental and inextricably interrelated issues limit understanding of ovarian malignancy. Clinically, we can neither recognize early lesions nor ascertain their potential. Hence, ovarian cancer management depends upon a “recognition/classification” paradigm wherein tumor recognition, classification and therapy depends upon the morphology of advanced lesions. There is a parallel inability to fully describe the participants and processes of early ovarian development, making it impossible to definitively exclude one or more of the three major theories on the ontogeny of ovarian tissues (1,2). Models and methods used to explore these problems have serious limitations. In carcinogenesis the early lesions are yet to be defined, while in ovarian embryology the minuscule size of the tissues involved and the limited numbers of participating cells restrict research opportunities.

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Authors and Affiliations

  1. Department of Pathology and Laboratory Medicine, University of Texas Medical School-Houston, USA

    Waldemar A. Schmidt

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  1. Waldemar A. Schmidt
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Editors and Affiliations

  1. University of Maryland, Baltimore, Maryland, USA

    Anne N. Hirshfield

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© 1989 Plenum Press, New York

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Schmidt, W.A. (1989). Ovarian Tumors, Stem Cells and Ontogeny: Imminentes Cognitiones . In: Hirshfield, A.N. (eds) Growth Factors and the Ovary. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5688-2_4

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  • DOI: https://doi.org/10.1007/978-1-4684-5688-2_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5690-5

  • Online ISBN: 978-1-4684-5688-2

  • eBook Packages: Springer Book Archive

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