Role of Anions in Platelet Intra Cellular Calcium Ion Rise and Arachidonic Acid Release Induced by Thrombin

  • Yukio Ozaki
  • Shoji Kume
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 255)


Calcium mobilization following agonist-receptor interactions has been shown to play a pivotal role in signal transduction in a variety of cells. Recently, it has been suggested that anion transport is closely associated with intracellular calcium rises; depletion of chloride ions from the extracellular medium suppressed calcium uptake and subsequent maturation of sea urchins, and more recently an anionsensitive Ca++ channel has been found in mouse pancreatic beta cells.


Arachidonic Acid Calcium Mobilization Arachidonic Acid Metabolite Arachidonic Acid Release Eicosatetraenoic Acid 
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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Yukio Ozaki
    • 1
  • Shoji Kume
    • 1
  1. 1.Dept. Clinical Central Lab.Yamanashi Medical CollegeYamanashi Pref.Japan

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