Role of Anions in Platelet Intra Cellular Calcium Ion Rise and Arachidonic Acid Release Induced by Thrombin
Calcium mobilization following agonist-receptor interactions has been shown to play a pivotal role in signal transduction in a variety of cells. Recently, it has been suggested that anion transport is closely associated with intracellular calcium rises; depletion of chloride ions from the extracellular medium suppressed calcium uptake and subsequent maturation of sea urchins, and more recently an anionsensitive Ca++ channel has been found in mouse pancreatic beta cells.
KeywordsArachidonic Acid Calcium Mobilization Arachidonic Acid Metabolite Arachidonic Acid Release Eicosatetraenoic Acid
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