The Role of Brain Protein Phosphatases 1 and 2A in the Regulation of Microtubule Assembly
Protein phosphatase C was purified from bovine brain and was considered to consist of 10 and 90 %, respectively, of the catalytic subunits of protein phosphatases 1 and 2A on the basis of the effects of ATP and inhibitor-2. We investigated the dephosphorylation of microtubule proteins and the autophosphorylated Ca2+/calmodulin-dependent protein kinase II (CaM kinase II) by protein phosphatase C.
KeywordsProtein Phosphatase Catalytic Subunit Bovine Brain Dependent Protein Kinase Microtubule Assembly
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