Significances of Two Different Mr Caldesmons

  • Kenji Sobue
  • Yasushi Fujio
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 255)


Regarding the Ca2+-dependent regulatory mechanism of the smooth muscle and nonmuscle actin-myosin interaction, the myosin-linked regulation based on phosphorylation of myosin by Ca2+- and calmodulindependent myosin light chain kinase and dephosphorylation by myosin phosphatase has been well documented (1–3). Despite the accumulation of several findings (4–7), however, the precise molecular mechanism of the actin-linked regulation is as yet unclear.


Myosin Light Chain Kinase Aortic Smooth Muscle Cell Contractile Element Phenotypic Modulation Expressional Change 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Kenji Sobue
    • 1
  • Yasushi Fujio
    • 1
  1. 1.Department of Neurochemistry and Neuropharmacology Biomedical Research CenterOsaka University Medical SchoolOsakaJapan

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