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Two Types of Mouse FM3A Cell Mutants Deficient in 5-Aminoimidazole-4-Carboxamide Ribonucleotide Transformylase and their Transformants Isolated by Human Chromosome-Mediated Gene Transfer

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Purine and Pyrimidine Metabolism in Man VI

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 253A))

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Abstract

Purine precursors used in the synthesis of nucleic acids are produced by a well-defined sequence of enzymatic reactions. The characterization of this pathway and its regulation in bacteria and lower eukaryotes has been due, in large part, to the availability of auxotrophic mutants defective in purine biosynthesis.

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References

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Author information

Authors and Affiliations

  1. Department of Immunology and Virology, Saitama Cancer Center Research Institute, Ina-machi, Saitama 362, Japan

    Dai Ayusawa & Kimiko Shimizu

  2. The Institute of Applied Microbiology, University of Tokyo, Bunkyou-ku, Tokyo 113, Japan

    Masatake Yamauchi & Michio Matsuhashi

  3. Department of Molecular Genetics, National Institute of Genetics, Mishima, Shizuoka 411, Japan

    Takeshi Seno

Authors
  1. Dai Ayusawa
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  2. Masatake Yamauchi
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  3. Kimiko Shimizu
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  4. Takeshi Seno
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  5. Michio Matsuhashi
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Editor information

Editors and Affiliations

  1. Mikanagi Gotanda Hospital, Tokyo, Japan

    Kiyonobu Mikanagi

  2. Tokyo Women’s Medical College, Tokyo, Japan

    Kusuki Nishioka

  3. University of Michigan Medical Center, Ann Arbor, Michigan, USA

    William N. Kelley

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© 1989 Plenum Press, New York

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Ayusawa, D., Yamauchi, M., Shimizu, K., Seno, T., Matsuhashi, M. (1989). Two Types of Mouse FM3A Cell Mutants Deficient in 5-Aminoimidazole-4-Carboxamide Ribonucleotide Transformylase and their Transformants Isolated by Human Chromosome-Mediated Gene Transfer. In: Mikanagi, K., Nishioka, K., Kelley, W.N. (eds) Purine and Pyrimidine Metabolism in Man VI. Advances in Experimental Medicine and Biology, vol 253A. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5673-8_87

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  • DOI: https://doi.org/10.1007/978-1-4684-5673-8_87

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5675-2

  • Online ISBN: 978-1-4684-5673-8

  • eBook Packages: Springer Book Archive

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