Is Gout Related to an Alteration of the Uric Acid Protein Binding?

  • Taddeo Anna
  • Morozzi Gabriella
  • Marcolongo Roberto
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 253A)


For more than a century, increased serum uric acid (U.A.) levels have been known to be a risk factor for gout1. However, although many hyperuricemic subjects have U.A. concentrations that exceed the estimate solubility of urate in serum, only about 25% of them appear to develop clinical gout2.


Uric Acid Serum Uric Acid Chronic Renal Disease Gouty Arthritis Gout Attack 
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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Taddeo Anna
    • 1
  • Morozzi Gabriella
    • 1
  • Marcolongo Roberto
    • 1
  1. 1.Institute of RheumatologyUniversity of SienaItaly

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