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Mechanism of Cell Partitioning; Equilibrium Contact Angle Measurements Predict Relative, Kinetic Partitioning Behaviour

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Separations Using Aqueous Phase Systems

Abstract

The relationships between cell partition, a dynamic process, and contact angle determinations, which are equilibrium thermodynamic measurements are investigated experimentally in biphasic systems of dextran and poly(ethylene glycol). Non-charge-sensitive partition, charge-sensitive partition and hydrophobic affinity cell partition all show correlations with contact angle measurements. Contact angles appear to provide a quantitative index of the degree of interaction of cells with the liquid-liquid interfaces of phase droplets which determine the kinetic features of partitioning.

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© 1989 Plenum Press, New York

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Youens, B.N., Cooper, W.D., Raymond, F.D., Gascoine, P.S., Fisher, D. (1989). Mechanism of Cell Partitioning; Equilibrium Contact Angle Measurements Predict Relative, Kinetic Partitioning Behaviour. In: Fisher, D., Sutherland, I.A. (eds) Separations Using Aqueous Phase Systems. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5667-7_43

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  • DOI: https://doi.org/10.1007/978-1-4684-5667-7_43

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5669-1

  • Online ISBN: 978-1-4684-5667-7

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