Relationship Between the Transfer Rate and the Difference in Partial Pressure of Gas Molecules at a Heterogeneous Interface

  • Masaji Mochizuki
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 248)


When a gas passes across a gas-liquid interface from the gas to liquid side, the gas molecule undergoes an increase of partial pressure at the liquid side because of its low solubility. Thus, in order for a molecule to cross the interface, it is necessary that the gas concentration at the liquid side is reduced below the equilibrium level. When the concentration falls, a discontinuity in the partial pressure inevitably occurs at the border because of difference in solubility. The relationship between the gap in partial pressure at the interface and the transfer rate is theoretically derived from the solubility difference, where the gap size is evaluated by dividing the transfer rate by the transfer coefficient, n. Comparing the theoretical and experimental n values obtained at the gas-liquid interface and red blood cell (RBC) boundary, the transfer rate across the heterogeneous interface is found to be proportional to the difference in partial pressure from the equilibrium level. In addition, conductivity, k, in aqueous solution at the interface is calculated to be 6.6 x 10−3 cm. see−1. Atn−1, regardless of gas type. Furthermore, for O2, CO2 and CO solubility in the RBC membrane is estimated to be about 22% of that in water, regardless of gas type.


Partial Pressure Transfer Rate Equilibrium Level Outward Direction Liquid Side 
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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Masaji Mochizuki
    • 1
  1. 1.Geriatric Respiratory Research CentreNishimaruyama Hospital064 Sapporo, Chuo-KuJapan

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