Structured Modeling and Simulation of Oxygen Transport to Hybridoma Cell in a Suspension Culture: Theoretical Analysis

  • Kyung A. Kang
  • Dewey D. Y. Ryu
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 248)


As the demand for monoclonal antibodies increases rapidly because of their diverse use for clinical and analytical application, and protein separation, monoclonal antibody production by hybridoma cell culture in large scale became necessary.


Oxygen Tension Myeloma Cell Oxygen Transport Oxygen Consumption Rate Dissolve Oxygen Tension 
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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Kyung A. Kang
    • 1
  • Dewey D. Y. Ryu
    • 1
  1. 1.Department of Chemical EngineeringUniversity of CaliforniaDavisUSA

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