Buffering of Muscle Tissue PO2 Levels by the Superposition of the Oxygen Field from Many Capillaries

  • Patricia A. Clark
  • Stephen P. Kennedy
  • Alfred ClarkJr.
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 248)


Characteristic of a Krogh (1919, 1929) analysis is a polygonal array of cells with oxygen supplied by capillaries at each cell vertex. Because of the symmetry of the arrangement, the assignment of tissue PO2 at any point can be thought of as the consequence of one particular capillary in the array. Thus the PO2 distribution in an entire muscle tissue sample is reduced to the analysis of a single Krogh cylinder. The Krogh analysis predicts substantial PO2 variation radially across a muscle as well as longitudinally running parallel to the capillary.


Cardiac Tissue Skeletal Tissue Tissue Cylinder Multicellular Tissue Shallow Variation 
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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Patricia A. Clark
    • 1
  • Stephen P. Kennedy
    • 1
  • Alfred ClarkJr.
    • 2
  1. 1.Mathematics, Rochester Institute of TechnologyRochesterUSA
  2. 2.Mechanical EngineeringUniversity of RochesterRochesterUSA

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