Abstract
The initial step in hair cell transduction involves coordinated flexion of an array of microvilli, the hair bundle, which gates a membrane conductance enabling a transducer current to flow into the cell (Hudspeth & Corey, 1977; Ohmori, 1985). Although the ionic selectivity of the transducer conductance is known (Corey & Hudspeth, 1979; Ohmori, 1985), the events leading to activation of the channel are not fully understood, and there is no consensus even on the precise form of relationship between bundle displacement and transducer current. Here we present some observations on the transduction process in turtle hair cells measured both directly in isolated cells under voltage clamp and indirectly from receptor potentials in the intact ear.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Art, J.J. & Fettiplace, R. (1987) Variation of membrane properties in hair cells isolated from the turtle cochlea. J. Physiol. 385, 207–242.
Art, J.J., Crawford, A.C. & Fettiplace, R. (1986) Ionic currents in solitary turtle hair cells. In: Auditory frequency selectivity (Eds: Moore, B.C.J. & Patterson, R.D.) Plenum Press, New York, pp. 81–88.
Corey, D.P. & Hudspeth, A.J. (1979) Ionic basis of the receptor potential in a vertebrate hair cell. Nature 281, 675–677.
Corey, D.P. & Hudspeth, A.J. (1983) Kinetics of the receptor current in bullfrog saccular hair cells. J. Neurosci. 3, 962–976.
Crawford, A.C. & Fettiplace, R. (1980) The frequency selectivity of auditory nerve fibres and hair cells in the cochlea of the turtle. J. Physiol. 306, 79–125.
Crawford, A.C. & Fettiplace, R. (1981) Non-linearities in the responses of turtle cochlear hair cells. J. Physiol. 315, 317–338.
Crawford, A.C. & Fettiplace, R. (1983) Auditory nerve responses to imposed displacements of the turtle basilar membrane. Hearing Res. 12, 199–208.
Crawford, A.C. & Fettiplace, R. (1985) The mechanical properties of ciliary bundles of turtle cochlear hair cells. J. Physiol. 364, 359–379.
Crawford, A.C. & Fettiplace, R. (1987) A substage cooling attachment for Zeiss IM microscopes. J. Physiol. 396, 13P.
Holton, T. & Hudspeth, A.J. (1986) The transduction channel of hair cells from bull-frog characterized by noise analysis. J. Physiol. 375, 195–227.
Hudspeth, A.J. & Corey, D.P. (1977) Sensitivity, polarity and conductance change in the response of vertebrate hair cells to controlled mechanical stimuli. Proc. Nat. Acad. Sci. U.S.A. 74, 2407–2411.
Ohmori, H. (1985) Mechano-electrical transduction currents in isolated vestibular hair cells. J.Physiol. 359, 189–217.
Ohmori, H. (1986) Gating properties of the mechano-electrical transducer channel in the dissociated vestibular hair cell of the chick. J. Physiol. 387, 589–609.
Russell, I.J., Cody, A.R. & Richardson, G.P. (1986) The responses of inner and outer hair cells in the basal turn of the guinea pig cochlea and in the mouse cochlea grown in vitro. Hearing Res. 22, 199–216.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1989 Plenum Press, New York
About this chapter
Cite this chapter
Fettiplace, R., Crawford, A.C. (1989). Mechano-Electrical Transduction in Turtle Hair Cells. In: Wilson, J.P., Kemp, D.T. (eds) Cochlear Mechanisms: Structure, Function, and Models. NATO ASI Series. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5640-0_12
Download citation
DOI: https://doi.org/10.1007/978-1-4684-5640-0_12
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-5642-4
Online ISBN: 978-1-4684-5640-0
eBook Packages: Springer Book Archive