Abstract
Finland is the country which has the highest incidence of Type I (insulin dependent) diabetes in the world. The age-adjusted annual incidence in 1977 to 1984 was 30 per 100,000 in the age group 0–15 years (1). Finland is also one of the countries in the world where the incidence of Type I diabetes is rapidly increasing. The latest data from 1986 to 1987 indicate that the incidence is now about 40 per 100,000 which means about 350 new cases per year.
Principal Investigators: H. K. Akerblom and J. Tuomilehto
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Akerblom, H.K., Reunanen, A., 1985, The epidemiology of insulin- dependent diabetes mellitus (IDDM) in Finland and in Northern Europe. Diabetes Care 8:Suppl. 1: 10–16.
Crumpton, M.J, 1987, HLA in medicine. Br Med Bull, 43: 1–240.
Walker, A., Cudworth, A.G., 1980, Type 1 (insulin dependent) diabetic multiplex families: Mode of genetic transmission. Diabetes 29: 1036–1039.
Wakisaka, A., Aizawa, M., Matsura, N. et al., 1976, HLA and juvenile diabetes mellitus in the Japanese. Lancet 2: 970.
Wolf, E., Tuomilehto, J., Cepaitis, Z., et al, (in preparation), A2, Cwl, Bw56, DR4 - a new haplotype increased in Type 1 diabetes in Finland.
Bentsson, B.O., Thompson, G., 1981, Measuring the strength of associations between HLA antigens and diseases. Tissue Antigen 18: 356–363.
Wolf, E., Spencer, K.M., Cudworth, A.G., 1983, The genetic susceptibility to Type 1 (insulin dependent) diabetes: Analysis of the DR association. Diabetologia 24: 224–230.
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© 1988 Plenum Press, New York
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Wolf, E., Tuomilehto, J., Luonamaa, R., The Study Group on Childhood Diabetes in Finland. (1988). Can the High Risk of Type I Diabetes in Finland be Explained by Familial Aggregation and by HLA Haplotype Distribution?. In: Camerini-Davalos, R.A., Cole, H.S. (eds) Prediabetes. Advances in Experimental Medicine and Biology, vol 246. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5616-5_29
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DOI: https://doi.org/10.1007/978-1-4684-5616-5_29
Publisher Name: Springer, Boston, MA
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