Abstract
It is now well established that human type I diabetes is a chronic autoimmune process characterized by a rather “silent” prediabetic stage of several months to years in duration. (1) An important issue in diabetes research is the identification during the prediabetic period of subjects I at high risk of developing diabetes. Several immunologic and metabolic parameters have been studied to assess their reliability as predictors of 5 future development of diabetes in high risk individuals. Even if the combination of several of these factors proves to be highly specific in I defining the high risk individuals these studies require a lengthy follow-up period to ascertain their sensitivity and reliability in predicting impending diabetes.
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© 1988 Plenum Press, New York
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Brayman, K.L., Markmann, J.F., Barker, C.F., Naji, A. (1988). Studies of Prediabetes in the Spontaneously Diabetic BB Rat. In: Camerini-Davalos, R.A., Cole, H.S. (eds) Prediabetes. Advances in Experimental Medicine and Biology, vol 246. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5616-5_11
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DOI: https://doi.org/10.1007/978-1-4684-5616-5_11
Publisher Name: Springer, Boston, MA
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