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The Hepatic Receptor for Asialoglycoproteins: Search for a Function

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Book cover Targeting of Drugs

Part of the book series: NATO ASI Series ((NSSA,volume 155))

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Abstract

During the last half decade increased interest has been directed towards an understanding of the mechanism whereby cell surface receptor expression is modulated. A number of receptors have become available for such examination, including the glucocorticoid receptor of hepatoma cells (Okret et al, 1986), the transferrin receptor in K562 cells (Rouault et al, 1985; Mattia et al, 1984), the EGF receptor in KB cells (Fearn and King, 1985), as well as the LDL receptor in rat hepatocytes (Ma et al, 1986; Larkin et al, 1985). In short, the expression of cell surface receptors has been shown to reflect regulatory mechanisms enabling the cell to adapt itself to changing metabolic priorities.

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© 1988 Plenum Press, New York

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Steer, J.C., Weiss, P., Wirth, P.J., Ashwell, G. (1988). The Hepatic Receptor for Asialoglycoproteins: Search for a Function. In: Gregoriadis, G., Poste, G. (eds) Targeting of Drugs. NATO ASI Series, vol 155. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5574-8_3

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  • DOI: https://doi.org/10.1007/978-1-4684-5574-8_3

  • Publisher Name: Springer, Boston, MA

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