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A Comparison of Methods for Analysis of mRNA in Hematopoietic Cells: Conventional and Clonal Northern Analysis and In Situ Hybridization

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Molecular Biology of Hemopoiesis

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 34))

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Abstract

Three methods for the detection of mRNA in hematopoietic cells are addressed, and examples using these techniques to examine human leukemic cells’ genetic response to chemical and biological response modifiers shown. The limitations and specific applications of the three techniques are discussed.

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© 1988 Plenum Press, New York

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Castiglia, C.L. (1988). A Comparison of Methods for Analysis of mRNA in Hematopoietic Cells: Conventional and Clonal Northern Analysis and In Situ Hybridization. In: Tavassoli, M., Zanjani, E.D., Ascensao, J.L., Abraham, N.G., Levine, A.S. (eds) Molecular Biology of Hemopoiesis. Advances in Experimental Medicine and Biology, vol 34. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5571-7_8

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  • DOI: https://doi.org/10.1007/978-1-4684-5571-7_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5573-1

  • Online ISBN: 978-1-4684-5571-7

  • eBook Packages: Springer Book Archive

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