Abstract
The mechanism of uptake of antigen by follicular dendritic cells (FDC) is poorly understood, but complement and preformed antibody have been shown to be necessary for this to process (1). Brown et al (2) suggested that lymphocytes may be involved in the active transport of antigen into follicles. More recent studies (3,4) have led to the suggestion that it may be marginal zone B cells which transport antigen into splenic follicles.
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© 1988 Plenum Press, New York
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Oldfield, S., Lortan, J.E., Hyatt, M.A.J., MacLennan, I.C.M. (1988). Marginal Zone B Cells and the Localisation of Antigen on Follicular Dendritic Cells. In: Fossum, S., Rolstad, B. (eds) Histophysiology of the Immune System. Advances in Experimental Medicine and Biology, vol 237. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5535-9_14
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DOI: https://doi.org/10.1007/978-1-4684-5535-9_14
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