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The Effects of Low O2 and Antioxidants on Steroidogenic Capacity in Cultured Rat Leydig Cells

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Regulation of Ovarian and Testicular Function

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 219))

Abstract

The development of methods for Leydig cell culture in a chemically defined medium has proven of considerable value to numerous investigators in recent years. It is now possible to study hormone action and control of Leydig cell steroidogenesis using such a system. Most investigators report that mature rat Leydig cells in culture remain viable for 7–10 days, however, function (LH/hCG binding to membrane receptors and testosterone production) is lost after 3–4 days (Mather et al., 1981; Browning et al., 1983).

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References

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© 1987 Plenum Press, New York

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Abney, T.O., Meyers, R.B. (1987). The Effects of Low O2 and Antioxidants on Steroidogenic Capacity in Cultured Rat Leydig Cells. In: Mahesh, V.B., Dhindsa, D.S., Anderson, E., Kalra, S.P. (eds) Regulation of Ovarian and Testicular Function. Advances in Experimental Medicine and Biology, vol 219. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5395-9_29

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  • DOI: https://doi.org/10.1007/978-1-4684-5395-9_29

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5397-3

  • Online ISBN: 978-1-4684-5395-9

  • eBook Packages: Springer Book Archive

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