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Organization of Peptidergic Afferents to the Striatum

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The Basal Ganglia II

Part of the book series: Advances in Behavioral Biology ((ABBI,volume 32))

Abstract

Radioimmunoassay and immunocytochemical methods have shown that the striatum contains some of the highest levels of various neuropeptides. Among these, enkephalin, dynorphin and substance P have been localized within the efferent projection neurons of the striatum, and somatostatin and neuropeptide Y within the interneuronal system of the striatum (Graybiel and Ragsdale, 1983). Although there is considerable body of knowledge of the organization of peptidergic neurons intrinsic to the striatum, information concerning the various sources of peptidergic afferents to the striatum and their organization within the striatum is fragmentary. In the following chapter we discuss the possible sources of peptidergic afferents to the striatum. The emphasis will be on those peptides whose distribution pattern in the central nervous system has been studied extensively and on those peptides that have been the focus of study in our laboratory.

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Authors and Affiliations

  1. Department of Neurology, Louisiana State University School of Medicine, New Orleans, La., USA

    Haitao Hu & A. Jayaraman

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  1. Haitao Hu
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  2. A. Jayaraman
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Editors and Affiliations

  1. Department of Anatomy F. Edward Hébert School of Medicine, Uniformed Services University, Bethesda, Maryland, USA

    Malcolm B. Carpenter

  2. Department of Neurology School of Medicine, Louisiana State University, New Orleans, Louisiana, USA

    A. Jayaraman

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© 1987 Plenum Press, New York

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Hu, H., Jayaraman, A. (1987). Organization of Peptidergic Afferents to the Striatum. In: Carpenter, M.B., Jayaraman, A. (eds) The Basal Ganglia II. Advances in Behavioral Biology, vol 32. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5347-8_3

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  • DOI: https://doi.org/10.1007/978-1-4684-5347-8_3

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