Abstract
Paneth cells are characteristically located at the bases of the crypts of Lieberkühn in the small intestine and contain prominent eosinophilic granules. Early studies associated them with a digestive purpose (1,2) and Paneth cells are curiously absent from the mucosa of some carnivores (3). More recent studies have suggested an antibacterial role. The secretory granules of the Paneth cells contain lysozyme (4,5), an enzyme with antibacterial properties (6,7). With ultrastructural studies, Erlandsen identified microorganisms in stages of digestion within phagolysosomes of rat Paneth cells (8,9).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Genderen, H.V. and Engel, C, Enzymologia 5, 71, 1938.
Klein, S., Am. J. Anat. 5, 315, 1906.
Wheeler, E.J. and Wheeler, J.K., Abstract, Anat. Rec. 148, 350, 1964.
Speece, A.J., J. Histochem. Cytochem. 12, 384, 1964.
Ghoos, Y. and Vantrappen, G., Histochem. J. 3, 175, 1971.
Amano, T., Inai, S., Seki, Y., Kashiba, S., Fujikawa, K. and Nishimura, S., Med. J. Osaka, Univ. 4, 401, 1954.
Noller, E.C. and Hartseil, S.E., J. Bacteriol. 81, 482, 1961.
Erlandsen, S.L. and Chase, D.G., J. Ultrastruc. Res. 41, 296, 1972.
Erlandsen, S.L. and Chase, D.G., J. Ultrastruc. Res. 41, 319, 1972.
Keren, D.F., Elliott, H.L., Brown, G.D., Yardley, J.H., Gastroenterology 68, 83, 1975.
Sandow, M.J. and Whitehead, R., Gut 20, 420, 1979.
Bohe, M., Borgstrom, A., Lindstrom, C. and Ohlsson, K., Digestion 30, 271, 1984.
Senegas-Balas, F., Falas, D., Verger, R., Histochemistry 81, 581, 1984.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1987 Plenum Press, New York
About this chapter
Cite this chapter
Kern, S.E., Keren, D.F., Beals, T.F., Varani, J. (1987). A Model for Paneth Cell Study: Tissue Culture of the Hyperplastic Paneth Cell Population of Rabbit Thiry-Vella Ileal Loops. In: Mestecky, J., McGhee, J.R., Bienenstock, J., Ogra, P.L. (eds) Recent Advances in Mucosal Immunology. Advances in Experimental Medicine and Biology, vol 216 A. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5344-7_48
Download citation
DOI: https://doi.org/10.1007/978-1-4684-5344-7_48
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-5346-1
Online ISBN: 978-1-4684-5344-7
eBook Packages: Springer Book Archive