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Recent Advances in Mucosal Immunology pp 257–265Cite as

The Role of Peyer’s Patches in Intestinal Humoral Immune Responses is Limited to Memory Formation

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 216 A))

Abstract

The interaction of antigens with the mucosal immune system in the gut has been studied extensively. It has become clear that depending on the type of antigen, the dose and the frequency of administration the immune response can vary between a state of tolerance (1,2) and extensive cellular or humoral reactivity (3–5). Peyer’s patches (PP) are thought to play a crucial role in the regulation of these immune responses. This function has been attributed to PP, e.g., by the presence of M cells (specialized epithelial cells in the follicle associated epithelium), which sample antigens from the gut lumen (6).

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Author information

Authors and Affiliations

  1. Department of Histology, Medical Faculty, Free University, P.O. Box 7161, 1007 MC, Amsterdam, The Netherlands

    S. H. M. Jeurissen, G. Kraal & T. Sminia

Authors
  1. S. H. M. Jeurissen
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  2. G. Kraal
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  3. T. Sminia
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Editor information

Editors and Affiliations

  1. University of Alabama at Birmingham, Birmingham, Alabama, USA

    Jiri Mestecky  & Jerry R. McGhee  & 

  2. McMaster University, Hamilton, Ontario, Canada

    John Bienenstock

  3. State University of New York at Buffalo, Buffalo, New York, USA

    Pearay L. Ogra

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© 1987 Plenum Press, New York

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Jeurissen, S.H.M., Kraal, G., Sminia, T. (1987). The Role of Peyer’s Patches in Intestinal Humoral Immune Responses is Limited to Memory Formation. In: Mestecky, J., McGhee, J.R., Bienenstock, J., Ogra, P.L. (eds) Recent Advances in Mucosal Immunology. Advances in Experimental Medicine and Biology, vol 216 A. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5344-7_30

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  • DOI: https://doi.org/10.1007/978-1-4684-5344-7_30

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5346-1

  • Online ISBN: 978-1-4684-5344-7

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