Abstract
Degeneration of lower motor neurons in the spinal cord and brain stem is a main phenomenon in ALS. These motor neurons occupy a remarkable position in that their cell bodies and dendrites are located within the central neurous system, whereas their axons constitute part of the peripheral nerves. The distal endings of the motor neurons in the motor end plates are unprotected by the blood-brain and blood-nerve barriers, and are therefore directly exposed to various substances in the blood.
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© 1987 Plenum Press, New York
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Conradi, S., Ronnevi, LO. (1987). Immunoglobulin-Mediated Cytotoxic Effect of ALS-Plasma Towards Erythrocytes: Reflexion of a Pathogenetic Mechanism?. In: Cosi, V., Kato, A.C., Parlette, W., Pinelli, P., Poloni, M. (eds) Amyotrophic Lateral Sclerosis. Advances in Experimental Medicine and Biology, vol 209. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5302-7_2
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DOI: https://doi.org/10.1007/978-1-4684-5302-7_2
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